SLP Flashcards

1
Q

Marcadores de maturidade B

A

CD19, 20, 79a

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2
Q

Marcadores de imaturidade

A

CD38, 34 e 10

TdT

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3
Q

Factor de bom prognóstico das leucemias agudas

A

Hiperdiploidipia (mais comum)

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4
Q

Diferença entre uma LLC naîve ou cél. memória

A

CD27+ nas memória

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5
Q

Análises duma LLC

A

Pancitopénia, leucocitose
Adenopatia
Hepatoesplenomegalia

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6
Q

Etiologia Linfoma folicular

A

> BCL-2 por translocação 14-18

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7
Q

Apresentação Linf. Folicular

A

Sintomas B + Adenopatias

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8
Q

Diagonóstico Linf.Folicular

A

Excisão Gg linfático e análise patológica

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9
Q

Apresentação Linfoma células Manto

A

Poliadenopatias (Anel waldeyer)

Hepatoesplenomegália

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10
Q

Etiologia Linf. Cel. Manto

A

Hiperproliferação Linfocítica por translocação 11-14 e > BCL-1

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11
Q

Apresentação Mieloma múltiplo

A

Hipercalcemia
Renal failure
Anemia
Fracturas patológicas

(CRAB)

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12
Q

Diagonóstico do Mieloma Múltiplo

A

Eletroforese (pico monoclonal) Sangue periférico e urina
Hemo e analítica
Mielograma

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13
Q

Proteinúria de Bence Jones

A

Excreção de cadeias leves das imunoglobulinas

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14
Q

O que se pretende visualizar na eletroforese de proteínas

A

Razão kappa/Lambda

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15
Q

Eritrodermia generalizada com adenopatias

A

Síndrome sezary - Leucemia linfócitos T

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16
Q

Dif. imunofenotípica entre Linf. Cel. Manto e Linfoma folicular

A

Linfoma Folicular: CD5 - e CD10, 38 +

Linf.Cel.Manto: CD5 + e CD10 -

17
Q

Marcador MM

A

CD38 e 138 + CD56