slide 10 Flashcards

1
Q

The citric acid cycle completes

A

the energy-yielding
oxidation of organic molecules (breakdown of
pyruvate) when oxygen is present

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2
Q

The citric acid cycle takes place in

A

the mitochondria

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3
Q

The citric acid cycle has 8 steps

A

each catalyzed by

a specific enzyme.

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4
Q

Before the citric acid cycle can begin pyruvate must first

A

bind to coenzyme A and become acetyl coenzyme A

acetyl CoA

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5
Q

The citric acid cycle produces

A

NADH from NAD+
and a related molecule FADH2
from FAD+.

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6
Q

NADH from NAD+
and a related molecule FADH2
from FAD+.

A

Both molecules are used in cellular respiration to

transport high energy electrons between reactions.

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7
Q

Citric Acid Cycle

A
Loss of 2 carbon per cycle
(4 per glucose) –
conversion to CO2
3 NADH made per cycle
(6 per glucose)
1 FADH2 made per cycle
(2 per glucose)
1 ATP made per cycle
(2 per glucose)
CoA regenerated
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8
Q

Oxidative phosphorylation has two components:

A

the

electron transport chain and chemiosmosis

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9
Q

Following glycolysis and the citric acid cycle, NADH and

FADH2 account for most of the energy extracted from food

A

These two electron carriers donate electrons to the electron
transport chain, which allows ATP synthesis via
chemiosmosis.

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10
Q

Oxidative phosphorylation

A

is a series of redox reactions

across the inner membrane of the mitochondria.

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11
Q

The electron transport chain is

comprised

A

of multiprotein
complexes spanning the inner
mitochodrial membrane

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12
Q

ELECTRON TRANSPORT CHAIN
The carriers alternate reduced
and oxidized states as they
accept and donate electrons

A

Electrons drop in free energy as
they go down the chain and are
finally passed to O2
, forming H2O.

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13
Q

The electron transport chain produces no ATP directly

A

At certain steps along the electron transport chain electron
transfer causes protein complexes to pump H+
from the
mitochondrial matrix to the intermembrane space.

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14
Q

ELECTRON TRANSPORT CHAIN

The resulting H+ gradient

A

– Stores energy
– Is referred to as a proton-motive force
– Drives chemiosmosis

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15
Q

Chemiosmosis

A

ATP synthase is the enzyme

that makes ATP

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16
Q

ATP synthase uses the H+

gradient

A

established by the
electron transport chain to
drive ATP synthesis

17
Q

During respiration, most energy flows in this sequence:

A
  • Glucose
  • NADH, FADH2
  • electron transport chain
  • proton gradient
  • ATP
18
Q

ATP synthesis has a high efficiency among reactions.

A

About 40% of the energy in a glucose molecule is
transferred to ATP during cellular respiration, making
approximately 32 ATP.
The remainder of energy is lost as heat

19
Q

Alternatives to Oxidative

Phosphorylation

A

fermentation

20
Q

Fermentation

A

enables some cells to produce ATP without

the use of oxygen or an electron transport chain

21
Q

Fermentation is an extension of glycolysis

A

in which ATP

is produced only by substrate-level phosphorylation.

22
Q

Alcohol fermentation (pyruvate converted to ethanol)

A

lactic acid fermentation (pyruvate converted to lactate) are

two examples

23
Q

Catabolic pathways

A
– Funnel electrons from
many kinds of organic
molecules into cellular
respiration
– Molecules other than
glucose can feed into
cellular respiration
24
Q

Cellular respiration is a
pathway controlled by
negative feedback.

A

If ATP concentration drops,

respiration speeds up

25
Q

Cellular respiration taps
energy that was stored in
food

A

by photosynthesis