sleep apnoea and narcolepsy

Question 1

what is obstructive sleep apnoea syndrome

Answer 1

recurrent episodes of upper airway obstricyion leadong to apnoea suring sleep 
usually associated w heavy snorinh
unrefreshing sleep
daytime somnolence/sleepiness 
poor daytime concentrayion

Question 2

why is OSAS important

Answer 2

impaired quality of life
marital dysbarmony
increased risk of RTAs - road traffic accidents
associated w hyoertension, increased risk of stroke and orobably increased risk if hesrt disease

Question 3

how is OSAS diagnoses

Answer 3

clinical history and examination 
epworty questionnaire 
overnight sleep study 
- pulse oximetry
- limited sleep studies 
- full polysomnography

Question 4

what does pomysomnograohy meaure

Answer 4

orobsal airflow
thoracoabdominal movement 
oximetru
body positkon 
EEG - brainwave recordings 
audiovisual recording
EOG
EMG - perioheral muscle
ECG

Question 5

what is narcolepsy

Answer 5

presents at younger age than sleep apnoea

associated w certian HLA types

Question 6

what are the clinical features of narcolepsy

Answer 6

cataplexy - where person suddenly collapses
excessuve daytime sombolence
hypnagogic/hypnopompic hallucinations
sleep paralysis

Question 7

what are the investigations of narcolepsy

Answer 7

PSG
MSLT ( >1 SOREM and mean sleep latency <8 mins)
low CSF orexin

Question 8

how do you treat narcolepsy

Answer 8

modafinal
decamphetamine
venlafaxine (for cataplexy)
sodium oxybate (xyrem)