Sleep- an introduction Flashcards

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1
Q

Definition of sleep?

A

A condition of body and mind which typically recurs for several hours every night, in which the nervous system is inactive, the eyes closed, the postural muscles relaxed, and consciousness practically suspended.

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2
Q

Do you lose perception of senses during sleep?

A

Our senses continue during sleep but the thalamus blocks sensory signals travelling to cortex where they’re normally consciously received.

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3
Q

Is sleep important?

A

Main functions of animals are well understood (eating, reproduction etc) but little understood about sleep as they can’t do these essential things when asleep.
‘if sleep doesn’t serve an absolutely vital function, it is the biggest mistake of the evolutionary process ever made’

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4
Q

What is unihemispheric sleep?

A

Some species have evolved the ability to uncouple the 2 hemispheres of the brain.

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5
Q

Which species have unihemispheric sleep?

A

Dolphins- maintain life necessary movement in the water.
Birds- 1 hemisphere and corresponding eye is open.

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6
Q

What is the evolutionary theory of sleep?

A

Inactivity at night is a survival function (being quiet keeps animals safe at night from others who are active).
Reduction of accidents in the dark and reduction of noise.

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7
Q

What is the energy conservation theory of sleep?

A

This is where the primary function of sleep is to reduce an animal’s energy demand and expenditure (provides inactivity so using less energy).

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8
Q

What is the purpose of hibernation?

A

In some animals, it acts as a means of conserving energy.

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9
Q

What is the restorative theory of sleep?

A

-sleep provides opportunity to repair and rejuvenate
-if deprived of sleep, lose immune function, die in weeks
-restorative functions like tissue repair and growth hormone release occur during sleep
-rate of cell division and protein synthesis increase
-restoring physiological functions
-restoring brain systems (REM)

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10
Q

What is the glymphatic system?

A

This drains toxins from the brain like lymphatic system and is more active during sleep (10-20x).

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11
Q

What do glial cells do during NREM sleep?

A

Glial cells distributed in brain in NREM sleep to increase space between neurons (allows cerebral spinal fluid to flush out toxins).

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12
Q

What is the Brain Plasticity theory?

A

Sleep is correlated to changes in structure and organisation of the brain (plasticity), critical for brain development in young people.
Sleep deprivation reduces ability to learn and perform tasks.

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13
Q

What is the mode of memory processing during sleep?

A

Favours memory consolidation that can’t occur when awake due to environ. demands

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14
Q

Which kinds of sleep are important for memory consolidation?

A

REM sleep previously thought as most important but now, slow wave sleep (SWS) is vital too

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15
Q

What is a electroencephalogram (EEG)?

A

This is used to investigate different types of sleep by determining different waveforms.

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16
Q

How is an EEG done?

A

Electrodes are placed on scalp and record electrical activity of brain. These distinct differences between sleep and awake states and are recorded.

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17
Q

Who developed the first sleep lab?

A

Kleitman- studied sleep deprivation and REM sleep.

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18
Q

How are brainwaves measured?

A

These are described by their frequency, measured in Hz

19
Q

What is a delta wave?

A

Occurs during sleep, 0.5-3.0 Hz

20
Q

What is a theta wave?

A

Occurs during sleep, 3.0-8.0 Hz

21
Q

What is an alpha wave?

A

Occurs when awake and resting, 8.0-12.0 Hz

22
Q

What is a beta wave?

A

Occurs when awake and doing cognitive tasks, 12.0-38.0 Hz

23
Q

What is a gamma wave?

A

Occurs when awake and at peak concentration, 38.0-42.0 Hz

24
Q

What are the stages of NREM sleep?

A

1) N1- Transition form wakefulness to sleep
2) N2- first unequivocal stage of sleep
3) N3- slow wave sleep

25
Q

What are the features of N1?

A

-1st 1-10 mins
-if woken, feel as though they didn’t sleep at all
-body muscles are functional
-breathing and heart rate slow and are regular
-blood pressure and temp decrease
-hypnogogic jerk

26
Q

What are the features of N2?

A

-10-25 mins
-heart rate slows
-body temp drops
-metabolic functions slow- prepare for deep sleep
-harder to wake sleeper

27
Q

What are the features of N3?

A

-35-45 mins
-deep sleep
-temp, breathing and heart rate at lowest level
-very hard to wake up
-feel disorientated if woken up
-dreaming may occur
-info processing and memory consolidation occur

28
Q

What are the features of REM sleep?

A

-after 90 mins sleep
-random and rapid eye movement
-absence of muscle tone (skeletal muscle paralysed- protective from acting out during dreams)
-vivd dreams
-heart, blood pressure and RR increase and irregular
-core temp poorly regulated

29
Q

What is sleep paralysis?

A

Disorder where patient awake during REM sleep and unable to speak or move.
Can come with terrifying hallucinations (sensation of suffocation or dread).

30
Q

How many hours of sleep does an adult require?

A

5-11 hours per night (average 7.75 hours).

31
Q

How many hours do short sleepers get?

A

Less than 6.5 hours a night (fall asleep quick and lose final REM)

32
Q

How many hours do long sleeps get?

A

Less than 9.5 hours a night (have an additional stage 2 and REM sleep).

33
Q

What is the relationship between age and hours of sleep?

A

As you get older, fewer hours are required.

34
Q

What is the relationship between age and REM sleep?

A

Fewer hours of REM as you get older.

35
Q

What societal changes cause sleep deprivation?

A

-Work ethic and shift patterns
-Early school start time
-24/7 entertainment

36
Q

What technological changes cause sleep deprivation?

A

-Artificial light
-Blue light- negative effects in children

37
Q

What are some consequences of sleep deprivation?

A

-reduced cog function
-reduced memory consolidation
-changes to apetite
-increased anxiety
-depression
-decreased sex drive

38
Q

What percentage of car accidents are sleep related?

A

20%

39
Q

What is a good bedtime routine?

A

-relaxing, avoid watching exciting film, wind down (listen to music and have a shower).
-go to bed same time every day. don’t nap, don’t go to bed unless sleepy

40
Q

What food and drink to avoid before bed?

A

-nicotine
-alcohol
-don’t eat a heavy meal
-reduce fluid intake
-caffeine

41
Q

Why should caffeine be avoided before bed?

A

This blocks adenosine receptor binding sites in brain (reduce sleep pressure)
Once caffeine subsides, high adenosine cause greater sleep pressure (crash)

42
Q

What is blue light?

A

Produced by LED and electronic devices.
This suppresses melatonin production

43
Q

Effects of exercise on sleep?

A

Exercise releases endorphins which can inhibit sleep so avoid a few hours before bed

44
Q

What technology can we use to investigate how well someone sleeps?

A

-patient history
-sleep diary
-sleep study (actigraphy, overnight oximetry)
-multichannel sleep recording
-full polysomnography