Sleep Flashcards
Almost complete loss of muscle tone in skeletal muscles
REM sleep
Important for the consolidation of memories
Associated with apnea, snoring, sleep paralysis and most dreaming
REM sleep
Divided into 4 stages; 4 being the deepest
Non REM sleep
Important for cellular repair
Associated with increased protein synthesis
Associated with sleep walking, sleep talking and bruxism
Non REM sleep
Theta activity
Stage 1
Sleep Spindle, K Complex
Stage 2
Delta Activity
Stage 3 and 4
Heart rate, respiration, penile erection _____ during REM sleep
increase
True or False? Electrical stimulation can trigger sleep and wakefulness.
True
Retinohypothalamic path: Light reduces (inhibits) _____ release from pineal gland.
melatonin
____ puts us to sleep
VLPO
____ keeps us awake
Orexin
____ coordinates it VLPO and Orexin
SCN
_____ SCN activity during the day (left) than at night (right)
Greater
_____ inhibits the gene encoding the hypothalamic orexin neuropeptides OX-1 and OX-2
suvorexant
Decreased Sleep leads to Increased _____ which leads to weight gain
ghrelin
a disorder of sleep attacks and excessive daytime sleepiness
caused by hypocretin deficiency (autoimmune attack on hypocretin (Orexin) neurons)
Narcolepsy
Genetics, age, and triggering infections or inflammation play important roles in the development of ______
narcolepsy
In individuals without narcolepsy and whose sleep is well regulated, ______ are released during wakefulness and increase activity in target neurons that promote wakefulness and suppress rapid-eye-movement (REM) sleep
hypocretins
In people who have narcolepsy with cataplexy, most of the ______ die off
hypocretin-producing neurons
10 sec respiratory pause
apnea
10 sec of a 50% decrease in breathing
hypopnea
an abnormal pattern of breathing characterized by progressively deeper and sometimes faster breathing, followed by a gradual decrease that results in a temporary stop in breathing called an apnea
Cheyne-Stokes respiration
associated with changing serum partial pressures of oxygen and carbon dioxide
Cheyne-Stokes respiration