Olfactory Flashcards
______ are embedded in a small area of specialized epithelium in the dorsal posterior recess of the nasal cavity.
Olfactory sensory neurons
Generation of receptor potentials takes place in the ____.
cilia
The mitral and tufted cells connect directly to the:
Anterior olfactory nucleus Olfactory tubercle Piriform cortex Amygdala Entorhinal cortex
The mitral and tufted cells connect indirectly to the:
Thalamus Hypothalamus Hippocampus Frontal cortex Orbitofrontal cortex
Odor-producing molecules are generally:
Small, containing 3 - 20 carbon atoms
Volatile
Water and lipid soluble
Odorant-binding proteins (OBP) concentrate odorants and transfer them across the mucus to the receptors.
What is the detection threshold for olfaction?
about 50 molecules
True or False? determination of differences in intensity is poor
True
True or False? Females have a better sense of smell than males
True
Activation of ______ are necessary for the full experience of certain smells, such as peppermint, menthol and chlorine
olfactory nociceptors
All olfactory receptors are coupled with ______
G-proteins
Some receptors act via _______; others act via ______
adenyl cyclase and CAMP; phospholipase C and the products of phosphatidylinositol hydrolysis
Olfactory receptors lead to the opening of ______ channels and ______
sodium; depolarization
Mitral and tufted cells send axons to the ______
olfactory cortex
The brain recognizes odors by the pattern of ______
glomerular activation
In the olfactory glomeruli, the periglomerular and granule cells produce ______; this sharpens and focuses olfactory signals
lateral inhibition
Olfactory adaptation is ______.
Rapid
Olfactory adaptation is specific for _____
a specific odor
True or False? Olfactory adaptation has both a central and peripheral phenomenon.
True
Peripheral adaptation may be mediated by ______ and ______ in the olfactory dendrites and ______
granule cells and/or beta kinase-2; beta arrestin-2; cilia
Olfaction triggers what two reflexes?
salivation and gastric secretions
Sneezing and lacrimation reflexes are triggered by ____
nose nociceptors
It is a structure in the nasal cavity concerned with odors that act as pheromones
Vomeronasal organ in animals
True or False? Pheromones, that typically come from urine or glandular secretions, influence reproductive and social behavior, such as estrus cycles, age of onset of puberty, implantation of fertilized embryos and mating behavior
True
True or False? The vomeronasal organ is not well developed in humans
True