Olfactory Flashcards
______ are embedded in a small area of specialized epithelium in the dorsal posterior recess of the nasal cavity.
Olfactory sensory neurons
Generation of receptor potentials takes place in the ____.
cilia
The mitral and tufted cells connect directly to the:
Anterior olfactory nucleus Olfactory tubercle Piriform cortex Amygdala Entorhinal cortex
The mitral and tufted cells connect indirectly to the:
Thalamus Hypothalamus Hippocampus Frontal cortex Orbitofrontal cortex
Odor-producing molecules are generally:
Small, containing 3 - 20 carbon atoms
Volatile
Water and lipid soluble
Odorant-binding proteins (OBP) concentrate odorants and transfer them across the mucus to the receptors.
What is the detection threshold for olfaction?
about 50 molecules
True or False? determination of differences in intensity is poor
True
True or False? Females have a better sense of smell than males
True
Activation of ______ are necessary for the full experience of certain smells, such as peppermint, menthol and chlorine
olfactory nociceptors
All olfactory receptors are coupled with ______
G-proteins
Some receptors act via _______; others act via ______
adenyl cyclase and CAMP; phospholipase C and the products of phosphatidylinositol hydrolysis
Olfactory receptors lead to the opening of ______ channels and ______
sodium; depolarization
Mitral and tufted cells send axons to the ______
olfactory cortex
The brain recognizes odors by the pattern of ______
glomerular activation
In the olfactory glomeruli, the periglomerular and granule cells produce ______; this sharpens and focuses olfactory signals
lateral inhibition