Olfactory Flashcards

1
Q

______ are embedded in a small area of specialized epithelium in the dorsal posterior recess of the nasal cavity.

A

Olfactory sensory neurons

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2
Q

Generation of receptor potentials takes place in the ____.

A

cilia

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3
Q

The mitral and tufted cells connect directly to the:

A
Anterior olfactory nucleus
Olfactory tubercle
Piriform cortex
Amygdala
Entorhinal cortex
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4
Q

The mitral and tufted cells connect indirectly to the:

A
Thalamus
Hypothalamus
Hippocampus
Frontal cortex
Orbitofrontal cortex
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5
Q

Odor-producing molecules are generally:

A

Small, containing 3 - 20 carbon atoms
Volatile
Water and lipid soluble
Odorant-binding proteins (OBP) concentrate odorants and transfer them across the mucus to the receptors.

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6
Q

What is the detection threshold for olfaction?

A

about 50 molecules

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7
Q

True or False? determination of differences in intensity is poor

A

True

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8
Q

True or False? Females have a better sense of smell than males

A

True

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9
Q

Activation of ______ are necessary for the full experience of certain smells, such as peppermint, menthol and chlorine

A

olfactory nociceptors

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10
Q

All olfactory receptors are coupled with ______

A

G-proteins

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11
Q

Some receptors act via _______; others act via ______

A

adenyl cyclase and CAMP; phospholipase C and the products of phosphatidylinositol hydrolysis

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12
Q

Olfactory receptors lead to the opening of ______ channels and ______

A

sodium; depolarization

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13
Q

Mitral and tufted cells send axons to the ______

A

olfactory cortex

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14
Q

The brain recognizes odors by the pattern of ______

A

glomerular activation

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15
Q

In the olfactory glomeruli, the periglomerular and granule cells produce ______; this sharpens and focuses olfactory signals

A

lateral inhibition

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16
Q

Olfactory adaptation is ______.

A

Rapid

17
Q

Olfactory adaptation is specific for _____

A

a specific odor

18
Q

True or False? Olfactory adaptation has both a central and peripheral phenomenon.

A

True

19
Q

Peripheral adaptation may be mediated by ______ and ______ in the olfactory dendrites and ______

A

granule cells and/or beta kinase-2; beta arrestin-2; cilia

20
Q

Olfaction triggers what two reflexes?

A

salivation and gastric secretions

21
Q

Sneezing and lacrimation reflexes are triggered by ____

A

nose nociceptors

22
Q

It is a structure in the nasal cavity concerned with odors that act as pheromones

A

Vomeronasal organ in animals

23
Q

True or False? Pheromones, that typically come from urine or glandular secretions, influence reproductive and social behavior, such as estrus cycles, age of onset of puberty, implantation of fertilized embryos and mating behavior

A

True

24
Q

True or False? The vomeronasal organ is not well developed in humans

A

True

25
Q

True or False? Subconscious activation of the hypothalamus by an estrogen-androgen odor mix can influence reproductive and other behaviors

A

True

26
Q

Decreased sense of smell

A

hyposmia

27
Q

Total lack of sense of smel

A

anosmia

28
Q

____ is a common symptom in Alzheimer’s disease.

A

Anosmia

29
Q

A distorted sense of smell

A

parosmia (dysosmia)

30
Q

Olfactory hallucinations

A

cacosmia