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Rheumatology > SLE/Scleroderma/Polymyositis/CTD/Sjogren > Flashcards

SLE/Scleroderma/Polymyositis/CTD/Sjogren Flashcards

1
Q

What symptom is present in 90% of people with scleroderma?

A

Raynaud’s phenomenon

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2
Q

What 2 parts of the body are most involved in polymyositis?

A

Pelvic girdle and shoulder girdle

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3
Q

How do you differentiate Jaccoud’s arthritis from RA?

A

Jaccoud’s is nonerosive

RA is erosive

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4
Q

What are gottron’s papules and what disorder is it seen in?

A

Scaly dermatitis over dorsum of hand seen in dermatomyositis

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5
Q

Difference between primary and secondary sjogrens

A 
Primary = no other rheumatologic disorders seen
Secondary = occurs with other rheumatologic disorders
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6
Q

What is CREST syndrome

A 
Calcinosis
Raynaud's 
Esophageal dysmotility
Sclerodactyly
Telangiectasia
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7
Q

What lab findings are specific for sjogren’s

A

Anti-SS-A (Ro)

Anti-SS-B (La)

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8
Q

What is sclerodactyly?

A

Thickening and tightness of skin of fingers and toes

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9
Q

What kind of exercises do you do for polymyositis/dermatomyositis - isometric, isotonic, or isokinetic exercises

A

Isometric

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10
Q

What medication can be used to treat raynaud’s?

A

Calcium channel blockers such as nifedipine

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11
Q

11 diagnostic criteria for SLE

A

DOPAMINe RASH

  1. Discoid rash
  2. Oral ulcers
  3. Photosensitivity
  4. ANA
  5. Malar rash
  6. Immunologic disorder
  7. Neurological disorder
  8. Renal disorder
  9. Arthritis
  10. Serositis
  11. Hematologic disorder
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12
Q

What always needs to be tested in someone who presents with polymyositis?

A

Swallowing function

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13
Q

What is seen with EMG for polymyositis

A

Myopathic changes which includes small amplitude, small duration with early recruitment, fibs, PSWs and CRDs

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14
Q

2nd line treatment for polymyositis/dermatomyositis

A

MTX or azathioprine

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15
Q

In children, is dermatomyositis or is polymyositis seen more often?

A

Dermatomyositis

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16
Q

What 2 antibodies are specific to Dx SLE?

A

Anti-Sm

Anti-dsDNA

17
Q

What is jaccoud’s arthritis

A

A type of arthritis seen in SLE that causes nonerosive changes of the fingers with ulnar deviation

18
Q

What precipitates eosinophilic fasciitis?

A

Strenuous exercises

19
Q

What glands are affected in Sjogrens?

A

Exocrine glands

20
Q

What is seen with muscle biopsy in polymyositis?

A

Perifascicular atrophy
Necrosis of type 1 and type 2 fibers
Variation in fiber size with large nuclei

21
Q

What antibody is positive for CREST syndrome?

A

Anti-centromere

22
Q

In polymyositis, what is involved first - pelvic girdle of shoulder girdle?

A

Pelvic girdle

23
Q

How do you treat eosinophilic fasciitis?

A

Steroids

24
Q

First line treatment for polymyositis/dermatomyositis

A

Steroids - 1mg/kg/day x 4-6 weeks

Rheumatology (12 decks)

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