Crystal Induced Synovitis Flashcards

1
Q

Gout vs pseudogout birefringence

A
Gout = negative
Pseudogout = positive
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2
Q

Treatment of pseudogout

A

NSAIDs
Steroids
Colchicine

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3
Q

What medications are used to treat acute and chronic attacks of gout?

A
Acute = colchicine, Indomethacin, steroids
Chronic = allopurinol, probenecid
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4
Q

Gout vs pseudogout: which is more likely to be monoarticular and which is more symmetric?

A
Gout = monoarticular
Pseudogout = symmetric
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5
Q

Radiologic findings of gout vs pseudogout

A
Gout = bony erosions near the tophi 
Pseudogout = punctate lines in the articular hyaline or fibrocartilage tissue
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6
Q

Most common joint involved in pseudogout

A

Knee

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7
Q

Crystals seen in gout vs pseudogout

A
Gout = monosodium urate crystals
Pseudogout = calcium pyrophosphate dihydrate
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8
Q

What medications can exacerbate a gouty attack?

A

ASA and thiazides

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9
Q

What 6 systemic diseases is pseudogout associated with?

A
"HA! 3-hypos and hyper"
Hemochromatosis
Amyloidosis
Hypothyroidism
Hyperparathyroidism
Hypomagnesemia
Hypophosphatemia
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10
Q

MOA of allopurinol vs probenecid

A
Allopurinol = decreases synthesis of Uric acid
Probenecid = increases secretion of uric acid
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11
Q

Which one shows more WBCs in joint aspirate: gout or pseudogout?

A

Gout - 15-25,000 WBCs

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