Deposition/storage Disease-related Arthritis

Question 1

What joints are most commonly affected in hemochromatosis

Answer 1

2nd and 3rd MCP and PIP joints

Question 2

Genetic inheritance of Wilson’s disease

Answer 2

Autosomal recessive

Question 3

What autosomal recessive deposition/storage disease is seen in ashkenazi Jews that results in glucocerebroside accumulation causing hip and knee degeneration

Answer 3

Gaucher’s disease

Question 4

Genetic inheritance of hemochromatosis

Answer 4

Autosomal recessive

Question 5

What do you treat Wilson’s disease with

Answer 5

Pencillamine

Question 6

Treatment of hemochromatosis

Answer 6

Phlebotomy and NSAIDs

Question 7

Someone presents with bluish discoloration of urine. What do you suspect?

Answer 7

Alkaptonuria

Question 8

Hemochromatosis is a disorder of excessive ___________ and deposition of ____________

Answer 8

Excessive iron stores and deposition of hemosiderin

Question 9

What is seen in eyes in Wilson’s disease

Answer 9

Kayser-fleischer rings