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Rheumatology > Rheumatoid Arthritis > Flashcards

Rheumatoid Arthritis Flashcards

1
Q

What causes the AA subluxation in RA?

A

Tenosynovitis of the transverse ligament of C1

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2
Q

What is Caplan’s syndrome

A

Rheumatoid pneumoconiosis.

People who are RF+ and develop intrapulmonary nodules.

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3
Q

How much space in the AA joint is considered abnormal?

A

Greater than 2.5 to 3 mm

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4
Q

Which way does the wrist deviate in RA?

A

Radially

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5
Q

Mechanism of boutonniere deformity

A

Weakness or rupture of terminal portion of extensor hood (tendon or central slip) at the PIP joint

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6
Q

What do you not want to use to treat a patient with RA who has rheumatoid nodules?

A

Methotrexate because it may enhance the development of accelerate the development of rheumatoid nodules

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7
Q

What is most specific and sensitive lab test for RA and is correlated with aggressive disease?

A

CCP

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8
Q

What ocular problem can people with RA develop?

A

Keratoconjunctivitis Sicca (dry eye)

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9
Q

What are the 7 ACR classification criteria for RA? And how long do you need to have symptoms for?

A

Need to have 4/7 of the following for 6 weeks:

  1. Symmetric involvement of joints
  2. 3 or joints involved
  3. Hand joint involvement
  4. RF positive
  5. Morning stiffness
  6. Rheumatoid nodules
  7. Radiographic changes
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10
Q

How do the carpal bones deviate in RA?

A

The proximal row of the carpal bones deviate in the volar direction.
The distal row deviates in the dorsal direction.

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11
Q

What are the 2 safest DMARDs in terms of toxicity?

A

Hydroxychloroquine and sulfasalazine

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12
Q

What kind of anemia is seen on CBC in RA?

A

Hypochromic microcytic anemia

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13
Q

Classic triad of felty’s syndrome

A

RA, splenomegaly, leukopenia

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14
Q

How do you treat mild, moderate and severe RA?

A 
Mild = NSAIDs and DMARD
Moderate = NSAIDs, DMARD, Steroid, Biologics
Severe = NSAIDs, 2 DMARDs, Steroid, biologics
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15
Q

Etanercept, Infliximab, and adalimumab are what class of DMARD?

A

Anti-TNF

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16
Q

Treatment of ulnar deviated MCPs

A

Ulnar deviation splint

17
Q

Membrane of granulation tissue that covers the articular cartilage at joint margins

A

Pannus

18
Q

Most common direction of AA subluxation in RA

A

Anterior AA subluxation

19
Q

What is the pseudobenediction sign and what causes it?

A

Inability to fully extend the 4th and 5th digits due to extensor tendon rupture because of the ulna drifting upwards causing abrasion and tearing of the extensor tendons to the 4th and 5th digits.

20
Q

How does the ulnar styloid deviate in RA?

A

Rotates dorsally creating a floating ulnar head

21
Q

Which DMARD can cause retinopathy and other eye problems?

A

Hydroxychloroquine

22
Q

What tendons are involved in dequervains

A

APL and EPB

23
Q

Which DMARD inhibits protein kinase JAK?

A

Tofacitinib

24
Q

What is the piano key sign?

A

Dorsally rotated ulnar styloid in RA creates an easily compressible elevated ulnar styloid

25
Q

MHC allele associated with RA

A

HLA-DR4

26
Q

Mechanism of swan neck deformity

A

Lax volar plate and contracture of finger muscles

27
Q

Mechanism of ulnar deviation at MCP

A

Ruptureo of Radial retinaculum

28
Q

What kind of exercises do people with RA do?

A

Isometric exercises

29
Q

What are 3 most commonly used DMARDs in RA treatment

A

MTX
Hydroxychloroquine
Sulfasalazine

30
Q

What cardiac problem can people with RA develop?

A

Pericarditis

31
Q

Correlation between RF and severity of RA

A

RF+ = increased severity of disease

32
Q

Protrusion acetabuli

A

Inward bulging of the acetabulum into pelvic cavity

33
Q

Viscosity, WBC, PMN %, and color of synovial fluid testing in RA

A 
Viscosity = low
WBC = 1000 - 75000
PMN = >70%
Color = transparent, cloudy
34
Q

What oral problem can people with RA develop?

A

Xerostomia

Rheumatology (12 decks)

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