SLE

Question 1

HLA Haplotypes associated with SLE

Answer 1

DR 2,3,4,8

Question 2

Which complement deficiency is associated with SLE

Answer 2

C1q Homogeneous

Question 3

Biopsy finding in class 1 of Lupus Nephritis

Answer 3

Normal or
Minimal change

Question 4

Biopsy finding in class 2 of Lupus nephritis

Answer 4

Mesangial lupus nephritis

Question 5

Biopsy finding in class 3 of Lupus nephritis

Answer 5

Focal Proliferative glomerulonephritis

Question 6

A patient comes with lupus nephritis, renal biopsy shows Diffuse Proliferative GN,
what is the class of lupus nephritis in this case?

Answer 6

Class 4

Question 7

Membranous glomerulonephritis on a renal biopsy of lupus patient denotes which lupus nephritis class?

Answer 7

Class 5

Question 8

Class 6 lupus nephritis shows……. In renal biopsy

Answer 8

Interstitial and tubular nephritis

Question 9

Management of CNS LUPUS (status epilepticus or coma)

Answer 9

pulse methylprednisolone, iv cyclophosphamide
and/or plasmapheresis.

Question 10

Drugs that are safe in pregnant lupus patients

Answer 10

Prednisone, azathioprine and hydroxychloroquine

Question 11

Serology of Sjogren’s syndrome

Answer 11

Ro +/- La

Question 12

Test used in diagnosis of Sjogren’s syndrome

Answer 12

Positive Schrimer’s

Question 13

Management of SLE

Answer 13

Steroids
DMRADS: Hydroxychloroquine (+eye examination)
AZA, cyclophosphamide