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Rheumatology > Inflammatory Myopathy > Flashcards

Inflammatory Myopathy Flashcards

1
Q

What is the antibody involved in incidents of Polymyositis and Dermatomyosistis?

A

Anti Jo 1 (Anti-Histidyl T RNA Synthetase)

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2
Q

How to differentiate between Dermatomyosistis and Polymyositis?

A

. Clinically
. Biopsy:
=DM: atrophic muscle fibers
=PM: infiltration of inflammatory cells (CD8 cells invading muscle fibers MHC1)

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3
Q

Tx of inflammatory myopathies

A

. Prednisone (+ bisphosphonates)

. Immunosuppressives (MAC)
*MTX
*AZA
*Cyclosporine

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4
Q

What is the inflammatory myopathy that is not responsive to steroids

A

Inclusion body myositis

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Rheumatology (14 decks)

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