Skin Structure (physiology) Flashcards
What makes up the epidermis ?
Stratified squamous (epithelium)
What body part have stratified squamous ?
Vaginal canal
Anus
Esophagus
What are the primary functions of the skin ?
Helps regulate temperature
Prevents loss of moisture
Provides a protective barrier against mechanical, thermal and physical injury.
Reduces harmful effects of UV radiation.
The skin is split into 3 main sections what are they ?
Epidermis
Dermis
Hypodermis
What’s the epidermis ?
It is the outermost layer of skin in the body.
Primary barrier between you and the outside world.
What does the epidermis consist of ?
Several layers of keritonised at various stages of keritinisation.
What is keratinization?
Process in which the cytoplasm of the outermost epidermal cells is replaced by keratin.
There are the 2 types of epidermis ?
Thick skin - usually free from hair.
Thin skin - hair is associated with it.
How many thick and thin layers are there?
4 thin
5 thick
What are the layers ?
Stratum basale
Forming the stratum spinosum, stratum granulosum, stratum lucidum ( only thick skin).
And stratum corneum (outer moist).
How long does it take for a keratinocyte to mature from the stratum basale tot he stratum corneum?
30 days
How is skin pigmentation caused ?
Caused by cells in the stratum basale called melanocytes.
These extend processes and fill keratinocytes with melanin.
The more cells they contract the more pigmented the skin becomes.
What is the main sensory cell in the stratum basale?
It’s the tactile epithelial (merkel) cell.
These are pale staining round cells that find free nerve ending and are accosted with the section of pain and itching.
What are the consequences of loss of melocytes?
Vitiligo occurs when pigment producing cells (melanocytes) die or stop producing melanin.
Involves patches of skin becoming lighter/ white.
What is the dermis?
The inner layer of the the two layer of the skin