Skin/soft Tissue

Question 1

What virus is associated with merkel cell carcinoma?

Answer 1

Polyomavirus

Question 2

What cancer stains positive for CK20 and NSE?

Answer 2

Merkel cell carcinoma

Question 3

What cancer stains positive for S100?

Answer 3

Melanoma

Question 4

What virus is associated with cervical, anal, oropharyngeal cancer, and what does the oropharyngeal ca stain positive for?

Answer 4

HPV; p16 positive

Question 5

What cancer is EBV associated with?

Answer 5

Nasopharyngeal ca, burkitts lymphoma, Hodgkin disease

Question 6

What cancer is HHV-8 associated with?

Answer 6

Kappas sarcoma

Question 7

What cancer is HTLV-1 associated with?

Answer 7

T cell leukemia

Question 8

What is Gorlin syndrome

Answer 8

Nevoid basal cell carcinoma syndrome
PTCH1 gene mutation
Autosomal dominant
Odontogenic keratocysts, multiple bcc, intracranial calcifications, rib and vertebral anomalies, distinct facies- frontal/temporal bossing, eye anomalies