Misc

Question 1

What is osteoconduction?

Answer 1

Prolonged process where cortical bone graft functions as nonviable scaffold for gradual ingrowth of blood vessels and osteoprogenitor cells from recipient site

Osteoconduction is essential for bone healing and regeneration.

Question 2

What is creeping substitution?

Answer 2

Gradual resorption and deposition of new bone (creeping substitution)

This method allows for the integration of the graft with the surrounding bone.

Question 3

What is osteogenesis?

Answer 3

New bone formation by surviving pre-osteoblasts and osteoblasts within the graft

Osteogenesis is a key process in bone healing and regeneration.

Question 4

What is the more prominent mechanism in the healing of cancellous bone grafts?

Answer 4

(Rapid revascularization)
Osteogenesis

Cancellous bone grafts heal more effectively due to faster blood vessel formation.

Question 5

Is osteogenesis also observed in the healing of vascularized bone grafts?

Answer 5

True

Osteogenesis occurs in both cancellous and vascularized bone graft healing.

Question 6

What is osteoinduction?

Answer 6

Transformation of local host mesenchymal cells into bone forming cells in the presence of inductive stimuli

Question 7

What regulates oateoinduction?

Answer 7

Insoluble polypeptide morphogens and enzymes (BMP etc)

Question 8

What does osteoinduction require prior to implantation?

Answer 8

Demineralization

Question 9

What syndrome includes hemangioblastomas of the retina and CNS, pheochromocytoma, and renal cell carcinoma

Answer 9

Von hippel lindau syndrome

Question 10

What does klippel trenaunay syndrome include?

Answer 10

Capillary and venous malformations, and limb hypertrophy (usually lower)
PIK3CA mutation

Question 11

What syndrome includes port wine stains, glaucoma, seizures and leptomeningeal angiomas

Answer 11

Sturge Weber syndrome

Question 12

What is osler Weber rendu syndrome

Answer 12

Hereditary hemorrhagic telangectasias
Can present with nose or GI bleeds, AV malformations of the lungs, liver, or brain
Inherited disorder ENG or ACVRL1

Question 13

What is cloves syndrome

Answer 13

Congenital lipomatous overgrowth, vascular malformations, epidermal nevi, and skeletal anomalies
Also PIK3CA mutation

Question 14

What is the MC tumor to Mets to the mandible in male vs female

Answer 14

Female- breast
Male- lung