Skin Neoplasia

Question 0

The ABCD’s of melanoma are…

Answer 0

Asymmetry, Border, Color, Diameter

Question 1

The official term for a common “mole”

Answer 1

Nevus

Question 2

A mole with a large white ring around it is called a…

Answer 2

Halo nevus

Question 3

A large, red, dome-shaped nodule. It likely can become malignant, so should be taken off.

Answer 3

Spitz nevus

Question 4

A deep nevus where pigmentation reaches deep into the dermis.

Answer 4

Blue nevus.

Question 5

Nevus found on the eye

Answer 5

ota nevus

Question 6

When isolated, these moles do not seem to have increased risk of melanoma. When multiple present, there is an increased risk.

Answer 6

Dysplastic nevus

Question 7

Cancer of melanocytes

Answer 7

melanoma

Question 8

Phrase meaning “still in epidermis”. If in this state, there isn’t risk of metastasis.

Answer 8

In situ

Question 9

Best indicator of probability of metastasis.

Answer 9

Breslow’s depth

Question 10

Process where you find the first lymph node of potential metastasis.

Answer 10

Sentinel lymph node biopsy

Question 11

Proliferation of keratinocytes that’s frequently benign. Incredibly common. Looks scaly on the mole in the picture

Answer 11

Seborrheic keratosis

Question 12

Non neoplastic cutaneous lesion with a “bag-like” tumor and stalk

Answer 12

Skin tag

Question 13

Down growth of epidermis into the skin, resulting in keratin deposit on the inside. Rupture easily and can become inflamed.

Answer 13

Epithelial cyst

Question 14

Benign neoplasm of epidermis that may precede squamous cell carcinoma. Induced by sunlight, results in hyperkeratosis

Answer 14

Actinic keratosis

Question 15

Cancer of the upper layers of skin epithelium, related to sun. Rarely metastasizes.

Answer 15

squamous cell carcinoma

Question 16

Cancer of the lower epidermal cell layers. Rarely metastasizes.

Answer 16

Basal cell carcinoma

Question 17

Hereditary condition resultiing in increased risk of hamartomas and malignancies. Results in mucosal papules and cobblestoning of the tongue.

Answer 17

Cowden’s syndrome

Question 18

Cowden’s syndrom results from a mutation in what gene?

Answer 18

PTEN (tumor suppressor gene)

Question 19

Acquired increase in sebaceous glands, usually on the face. non-neoplastic

Answer 19

Sebaceous hyperplasia

Question 20

Benign neoplasm of sebaceous glands

Answer 20

Sebaceous adenoma

Question 21

Malignant neoplasm of sebaceous glands

Answer 21

Sebaceous carcinoma

Question 22

Condition resulting in an increased risk of sebaceous adenoma or carcinoma, as well as keratoacanthomas

Answer 22

Muir-Torre syndrome

Question 23

Muir-torre syndrome results from mutations in what genes?

Answer 23

MLH1, MSH2 (DNA mismatch repair genes)