Antiarthritic Drugs Flashcards
0
Q
Inhibits macrophages, maybe TLR9 in dendritic cells
A
Hydroxychloroquine
1
Q
Folate metabolism inhibitor (T and B cell)
A
Methotrexate
2
Q
Pyrimidine synthesis inhibitor in T cells
A
Leflunomide
3
Q
Inhibits COX and scavenges free radicals
A
Sulfasalazine
4
Q
Reduces macrophage phagocytosis and affects antigen presenting cells & T cells
A
Gold
5
Q
Blocks DNA synthesis, primary site of action T cell
A
Azathioprine
6
Q
Calcineurin inhibitor to inhibit T cell activation
A
Cyclosporine
7
Q
Block TNF action (2 drugs)
A
Etanercept, Inflixumab
8
Q
Interleukin 1 receptor antagonist
A
Anakinra
9
Q
Blocks T cell activation by antigen presenting cell (CD80)
A
Abatacept
10
Q
Blocks B cell activation
A
Ritixumab
