skin last min Flashcards

1
Q

which layer contains melanocytes?

A

Stratum basale

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2
Q

which layer contains ketatin

A

Stratum spinosum

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3
Q

Stratum corneum

Cells in this row

function

A

Corneocytes - horny cells

dead keratinocytes,
give structure
chemical barrier
water resistant

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4
Q

stratum lucidum

A

clear layer in soles and palms of hands and feet

transparent cells

reduce friction between
stratum granulosum and corneum

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5
Q

Stratum Granulusoum

cells

A

flat cells, no nuclei, allow them to have lots of keratin, hard rigid layer

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6
Q

which layer makes keratin

A

stratum spinosum

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7
Q

which layer makes melanocytes

A

stratum basale

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8
Q

Dermis

3 structural properties

A

-fibrous
-made of CT
-made of crosslinking collagen and elastin fibers

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9
Q

2 layers of dermis

A

Papillary layer
Reticular Layer

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10
Q

Dermis Layers Composition

Papillary Layer

A

highly vascular, loose, CT.

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11
Q

Dermis Layers Composition

Reticular Layer

A

Thick, dense, CT
Majority of layer

contains nerves, vessels, follicles, glands

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12
Q

Ehlers-Danlos Syndrome

Defect in what?

A

Collagen

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13
Q

Ehlers-Danlos Syndrome

What is seen on physical exam?

A

Hypermobility of joints bc weak CT

Elastic skin

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14
Q

Ehlers-Danlos Syndrome
Secondary Problems

A

Scoliosis/kyphosis
Ruptured arteries and organs
Thin corneas

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15
Q

Marfan syndrome

Defect in what?

A

Connective Tissue

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16
Q

Marfan syndrome

Cause?

A

FIBRILIN1 mutation

Codes for fibrillin and the elastic fibers of CT

17
Q

Marfan Syndrome Appearance

A

Long narrow face
Tall thin build
digits long
scoliosis 60%
Sternum defects

18
Q

_____% of people with Marfans develop changes in heart and vessels.

A

90

19
Q

Marfans

Aortic aneurysm

A

Walls of aorta, become weak, bulge out and could rupture.

Usually aortic root

20
Q

Marfans

Aortic dissection

A

Aorta tear, blood enters middle level
possible rupture

21
Q

Marfans

Heart valve problems

A

weak valve, regrug

22
Q

Squamous Cell carcinoma

Which layer and color

A

red elevation on skin

Stratum spinosum

Metastasize if not removed

23
Q

Basal cell carcinoma

shape

% cure
% white ppl

A

Basal cell layer

DOme shape forms ulcer

99% curable
30% white

24
Q

Melanoma

Layer?

% of skin cancers

Chance of survival is poor if the lesion

A

basal

5%

> 4mm