Skin infections and genetics Flashcards

1
Q

What is acyclovir

A

Anti viral

good for cold sores and shingles

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2
Q

What does Herpes simplex virus cause?

A

Gingiovostomatitis in kiddies that lasts around a week

( cold sores)

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3
Q

How do you treat lice?

A

malathion

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4
Q

What skin infections can strep pyogenes cause ?

(group A strep)

A

Infected eczema

Impetigo

Cellulitis

Erysipelas

Necrotising fasciitis

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5
Q

In leg ulcers which organisims in particular are worth treating?

A

Strep.pyogenes

Staph. aureus

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6
Q

What is Orf?

A

Firm, fleshy nodule on the hands of sheep farmers

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7
Q

What disease can Coxsackie virus cause?

A

Hand, foot and mouth disease

and

Herpangina

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8
Q

What is molluscum contagiosum?

A

Fleshy, firm, umbilicated pearlescent nodules which are common in children and are self limiting , take a couple months to disappear

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9
Q

Where do you find candida skin infections?

A

In skin folds where it is warm and moist

i.e

Under the breast, around the groin, abdominal skin folds

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10
Q

What causes Lyme disease?

A

Borrelia burgdorferi transmitted by ticks

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11
Q

How do you treat Syphilis?

A

Penicillin injections

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12
Q

What is trichophyton rubrum?

A

It is the most common Dermatophyte

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13
Q

When would swabbing a leg ulcer be appropriate?

A

Only if signs of cellutlitis or infection are present

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14
Q

What are the two important kinds of Staphylococcus?

A

Coagulase positive and Coagulase negative

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15
Q

What does parvovirus B19 cause?

A

Erythema infectiosum

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16
Q

Where do scabies tipically make burows?

A

Finger webs

Wrists

Genital area

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17
Q

What are the complication of erythema infectiosum

A

Arthritis

Chronic anaemia

Aplastic crises

Spontaneous abortion

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18
Q
A
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19
Q

How does Aciclovir work?

A

It is an analogue of Guanosine so the VZV and HSV take it up to use in DNA but then get fucked and cant replicate

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20
Q

What are the three important classes of streptococcus?

A

Alpha-haemolytic ( partial haemolysis)

Beta-haemolytic (complete haemolysis)

Gamma (non- haemolytic)

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21
Q

How would you treat Necrotisnig Fasciitis?

A

Surgical debridement and antibiotics

Its life threatenting

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22
Q

What is this?

A

Zoster of the mandibular division of the facial nerve

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23
Q

What is the name for gram positivie staphylococci which is coagulase positive?

A

Staph. aureus

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24
Q

Where would you find tinea cruris?

A

Pubic area

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25
What kind of vaccine is the chickenpox vaccine and who gets it ?
Live attentuated vaccine used in susceptible health care works and a higher dosage version for oldies
26
How would you confirm a diagnosis of Erythema infectiosum?
Testing for Parvovirus B 19 IgM test
27
What are the two treatment options for dermatophyte scalp infections?
Terbinafine orally or Itracnoazole orally
28
What are the three phases of a syphilis infection?
Primary - Chancre Secondary- red rash over body + "snail track" ulcers Tertiary- CNS, cardiovasclar etc
29
What is this?
Zoster of the maxiallry division of the trigeminal nerve
30
What antibiotic would be used for staph aureus infections?
Flucloxacillin
31
What skin infections can staph. aureus cause?
Boils and Carbuncles Cellulitis Infected eczema Impetigo wound infections
32
How does lyme disease present ?
Erythema Migrans
33
How long is the incubation period for scabies?
6 weeks
34
What is the medical name for ring worms?
Tinea corporis
35
What is the correct term for instances when the pain from shingles lasts more than 4 weeks longer than the rash
Post herpetic neuralgia
36
What is the order of evolution of the spots in chickenpox?
Macules papules vesicles scabs recovery
37
How would you confirm a diagnosis of candida skin infection and what would you use to treat it ?
Swab for culture Clotrimazole cream Oral fluconazole
38
What does Pediculus mean?
Louse
39
What nerve is affected in Opthalmic Zoster?
Opthalmic division of the trigeminal nerve
40
What is this and what causes it ?
Erysipelas caused by strep pyogenes
41
What are the possible complications of chickenpoxs to be aware of?
Secondary bacterial infection Penumonitis Scarring Encephalitis
42
Where would you find strep. viridians?
Commensals of the mouth, throat and vagina Viridians for Vagina
43
44
What antibiotics would you use in lyme disease?
Doxycycline or Amoxicillin
45
What is Herpangina?
Blistering rash of the back of the mouth
46
What is Ramsay-hunt syndrome?
Vesicles and pain in the auditory canal and throat. Palsy of the facial nerve irritation of the vestibulocochlear nerve resulting in Deafness, vertigo and tinnitus
47
How would you treat scabies?
Malathion lotion applied over night to the whole body and then washed off the next day
48
How can you treat molluscum contagiosum?
With liquid nitrogen
49
What is the go to treatment for small dermatophyte skin infections?
Clotrimazole
50
What causes syphilis?
Bacterial infection - Treponema pallidum
51
What happens if you dont catch Lyme disease early?
Heart block Nerve palsies Arthritis
52
What type of HPV is most common in warts/verrucas?
types 1 - 4
53
What virus is responsible for chicken pox and Shingles?
Varicella Zoster virus Chickenpox is Varicella Shingles is Zoster
54
What antibiotic would be used in strep. pyogenes?
Penicillin
55
What causes Herpangina?
Coxsackie virus or Echovirus
56
What is the name for gram positivie staphylococci which is coagulase negative?
Staph. Epidermidis
57
What is Necrotising Faciitis?
Bacterial infection spreading long fascial planes
58
What is this?
Scabies
59
Which types of HPV cause genital warts?
type 6 and type 11
60
What are the two types of necrotising faciitis?
type I - mixed anaerobes and coliforms (think post abdominal surgery) Type II - Group A strep (strep. pyogenes)
61
Which type of HPV is most common in cervical cancer?
Types 16 and 18
62
Where would you find tinea manuum?
On the hands
63
64
What is this?
Periungual Fibromata
65
What is this sign called?
Longitudinal ridging
66
What is the diagnosis?
Tuberose Sclerosis
67
What kinds of things do people with Tuberose Sclerosis get?
Infantile seizures Ash leaf macules Periungual fibromas Facial angiofibromas Hamartomas and bone cysts
68
How is Tuberose Sclerosis passed on?
Autosomal Dominant
69
What is the Diagnosis ? Born at term, some skin loss noted on delivery 24 hrs later widespread blistering and skin loss which progressed to extensive skin loss with any movement or handling of the baby
Epidermolysis Bullosa
70
What are the thee main types of Epidermolysis Bullosa?
Simplex ( Epidermis only) Junctional (Dermo-epidermal Junction) Dystrophic (Dermis)
71
Whats the diagnosis ? greater than 5 Cafe au lait macules Axillary freckles
Neurofibromatosis type 1