SKIN INFECTION Flashcards
Flat lesions charcterized by change in color of the affected skin.
MACULES
Raised lesions, solid in consistency of less than 5 mm in diameter
PAPULES
Flat with elevated surface ( plateau-like) with more than 5 mm diameter
PLAQUES
Rounded raised lesions more than 5 mm in diameter
NODULES
Annular or ring like papules or plaques with pinkish color
URTICARIA ( wheals or hives)
Circumscribed fluid-filled lesions less than 5mmin diameter
VESICLES
circumscribed fluid-filled lesions more than 5mm in diameter
BULLAE
Circumscribed, exudate-filled lesions
PUSTULES
Skin lesions due to bleeding into the skin.
PURPURA
a.Petechiae - less than 3 mm diameter
b.Ecchymosis - more than 3 mm diameter
Crater- like lesion thay may involve the deeper layers of the epidermis and dermis
ULCER
Necrotic ulcer covered with a blackened scab or crust
ESCHAR
A pyogenic (pus-producing) infection involving the hair follicle. It is charavterized by localized painful inflammation and heals rapidly after draining the pus.
FOLLICULITIS
An extension of folliculitis and also known as boil. It is characterized by LARGER AND PAINFUL NODULES with underlying collection of dead and necrotic tissue.
FURUNCLE
Represents a coalescence of furuncles that extends into the subcutanueous tissue with multiple sinus tracts.
CARBUNCLE
Folliculitis occuring at the base of the eyelids
STY OR HORDEOLUM
Common in children. Primarily involves the face and the limbs. Starts as macule, then becomes a pus-filled vesicle that ruptures and forms crust(honey colored crust)
IMPETIGO
Part of the normal flora of the skin and commonly associated with “stitch abscess”, UTI, and Endocarditis. Causes infections in individuals with prosthetic devices.
STAPHYLOCOCCUS EPIDERMIS
Gram stain of samples of infected tissue will show gram- positive cocci in pairs and chains associated with leukocytes
MICROSCOPY
Positive beta hemolysis in blood agar.
CULTURE
Antibiotic susceptibility test with (+) zone of inhibition of growth around the bacitracin disc.
BASITRACIN TEST
Capable of producing water- soluble pigments. An opportunistic pathogen, a common cause of nosocomial infections(hospital-acquired) and resistant to most antibiotics.
PSEDOMONAS AERUGINOSA
Warts are caused by a DNA virus, the
HUMAN PAPILLOMAVIRUS
HPV is acquired by?
- Direct contact through mucosal or skin breaks.
2.sexual contact.
3.passage through infected birth canal.
Benign, self limiting proliferation of the skin that undergoes spontaneous resolution.
SKIN WARTS
Also known as condylomata acuminata
GENITAL AND ANOGENITAL WARTS
Treatment for Warts is by removal of the lesion by:
1.surgical excision
2.cryosurgery
3.electrocautery
4.application of caustic agents
Etiologic agents for Herpes Simples Infections
Herpes Simples Virus ( HSV) Types 1 and 2, (herpesviridae)
Herpes Simplex Virus can be transmittef through:
1.oral contact ( kissing)
2.fomites (sharing of glasses, toothbrushes)
3.sexual contact
4.transplacental ( during pregnancy) (during childbirth)
Primary infection, primarily caused by HSV-1. Presents as vesicles that rupture and ulcerate. Seen in the buccal mucosa, palate, gingivae, pharynx, and the tongue. GINGIVITIS. Common furing childhood.
GINGIVOSTOMATITIS
Caused by HSV-1 and HSV 2. Usually located at the vermillion boarders of the lips.
HERPES LABIALIS ( fever blister or cold sore)
HSV infection involving the fingers and caused by both HSV types 1 and 2.
HERPETIC WHITLOW
HSV Infection occuring in children with eczema.
ECZEMA HERPETICUM
HSV infection of the body and is usually acquired during wrestling or playing rugby.
HERPES GLADIATORUM
Skin infections may be caused by a variety of infectious agents such as:
Bacteria, Viruses, Fungi
A common cause of stitch abscess.
STAPHYLOCOCCUS EPIDERMIDIS
Grape-like clusters
Staphylococcus aureus
Treatment choice for Staphylococcus aureus
BETA-LACTAM ANTIBIOTICS such as “Penicillin”
Part of the normal flora of the skin and commonly associated with “stitch abscess” ,UTI, and endocarditis
STAPHYLOCOCCUS EPIDERMIDIS
Pyoderma
Impetigo - lesions rupture and form honey-colored crusts
Clinical findings for STREPTOCOCCUS PYOGENES
1.impetigo
2.erysipelas
3.cellulitis
4.necrotizing fasciitis
Also known as “flesh-eating” or “streptococcal gangrene”
NECROTIZING FASCIITIS
TINEA VERSICOLOR is caused by
MALASSEZIA FURFUR
MALASSERIA FURFUR IS A NORMAL FLORA of the skin particurly in areas rich in sebaceous glands.
TRUE
The lesions are scaly with a dry, chalky appearance, usually appear on the face, neck, trunk ans arms.
TINEA VERSICOLOR
___________ are gram positive bacilli arranged individually or in pairs or long serpentine chains giving them characteristic “bamboo fishing rod” or “Medusa head” appearance.
BACILLUS ANTHACIS
Mode of transmission of Bacillus Anthracis
Through inoculation into open skin from either the soil or infected animal products, ingestion of infected meat or milk, inhalation of aerosolized spores.
It produces four lethal toxins namely; alpha, beta, iota, and epsilon toxins.
CLOSTRIDIUM PERFRINGENS
A life-threatening infection following physical trauma or surgery characterized by massive tissue necrosis with gas formation, shock, renal failure, and death within 2 days of onset
GAS GANGRENE
Fungal infections involving the keratinized structures of the body such as the skin, hair, and nails.
CUTANEOUS MYCOSES OR DERMATOPHYTOSIS
Caused of “CUTANEOUS MYCOSES”
Caused by a group of fungi reffered as “DERMATOPHYTES”
Dermatophytes produce ________ an enzyme capable of breaking down keratin.
KERATINASE
Infect the hair and nails only
MICROSPORUM
Infect the skin, hair and nails.
TRICHOPHYTON
Infect only the skin and nails.
EPIDERMOPHYTON
DERMATOPHYTES are classified as
1.ZOOPHILIC ( From animals to humans)
2.GEOPHILIC ( from soil to humans)
3.ANTHROPOPHILIC ( From humans to humans)
Also known as Athlete’ foot
TINEA PEDIS
scalp
TINEA CAPITIS
Body
Tinea Corporis
Tinea cruris or jock itch is in
GROIN
TINEA MANUS
Hands
Tinea Barbae is in
BEARD
TINEA UNGUIUM also known as ONYCHOMYCOSIS
NAILS
Tinea involving the skin usually presents with a ________ pattern
RING WORM
TREATMENT FOR CUTANEOUS MYCOSES
ANTINFUNGAK DRUGS SUCH AS “AZOLES” Micronazole, clotrimazole, econazole.
The infection initially involves the deeper layers of the dermis and subcutaneous tissue then later the bones.
SUBCUTANEOUS MYCOSES
Also known as rose gardener’s disease.
SPOROTRICHOSIS
Sporotrichosis is caused by a dimorphic fungus called
SPOROTHRIX SCHENCKII ( found in the soil and decaying vegetation.
Characterized by verrucous nodules or plaques. The infection in insidious and may become chronic.
CHROMOBLASTOMYCOSIS
Mycetoma or Madura Foot common cause are
Phaeoacremonium, Madurella, Curvularia, and Fusarium.
also known as Madura foot, is a chronic, progressively destructive disease that primarily affects the skin, subcutaneous tissues, and bones. It typically involves the feet but can also affect other parts of the body.
Mycetoma
small, benign growths on the skin caused by an infection with human papillomavirus (HPV). They can appear anywhere on the body and are common, particularly among children and young adults.
WARTS
A sexually transmitted form of warts that appear in the genital and anal areas.
GENITAL WARTS ( CONDYLOMATA ACUMINATA)
Found on the soles of the feet. These warts can be painful due to their location and are often flat due to pressure from walking.
PLANTSR WARTS
Long, thread-like warts that typically appear on the face, especially around the mouth, eyes, and nose.
Filiform Warts
Many warts resolve on their own over time, but treatment can speed up the process and alleviate discomfort:
Topical Treatments:Salicylic Acid: Over-the-counter treatments that exfoliate the infected skin.Cantharidin: Applied by a healthcare provider to create a blister under the wart.Cryotherapy: Freezing the wart with liquid nitrogen, often done by a healthcare professional.Electrosurgery and Curettage: Burning off the wart with an electric current and then scraping it away.Laser Treatment: Using laser energy to destroy wart tissue.Immunotherapy: Applying medications or solutions that stimulate the immune system to fight the wart virus.
Herpes simplex infections are caused by the
herpes simplex virus (HSV), which is categorized into two types: HSV-1 and HSV-2
Commonly causes oral herpes, which results in cold sores or fever blisters around the mouth.Can also cause genital herpes, although this is less common.
HSV-1 (Herpes Simplex Virus Type 1)
Primarily causes genital herpes, which results in sores and blisters around the genital and anal areas.Less commonly, it can cause oral herpes.
HSV-2 (Herpes Simplex Virus Type 2)
Painful blisters or sores on the lips, mouth, gums, or throat.May be accompanied by fever and swollen lymph nodes.
Oral Herpes (HSV-1)
Painful blisters or sores on the genitals, buttocks, thighs, or anus.Symptoms may include itching, pain during urination, and discharge.
Genital Herpes (HSV-2):
Affects only the outermost layer of the skin (stratum corneum) and hair shafts.Examples: Pityriasis versicolor, Tinea nigra.
Superficial Mycosis:
Involves the deeper layers of the skin, subcutaneous tissue, and sometimes bone.Examples: Sporotrichosis, Chromoblastomycosis.
Subcutaneous Mycosis:
Affects the epidermis, hair, and nails.Commonly caused by dermatophytes (e.g., Trichophyton, Microsporum, Epidermophyton).Example: Tinea corporis (ringworm of the body), which matches the patient’s symptoms.
Cutaneous Mycosis
Involves internal organs and can affect multiple systems in the body.Examples: Histoplasmosis, Coccidioidomycosis.
Systemic Mycosis
a viral infection of the upper respiratory tract, primarily caused by rhinoviruses. It is highly prevalent and affects people of all ages, typically leading to mild symptoms.
Common cold
The most common cause, responsible for about 50% of colds.
Rhinoviruses
caused by the novel coronavirus SARS-CoV-2, emerged in late 2019 and led to a global pandemic. It affects the respiratory system and can cause a range of symptoms from mild to severe, including life-threatening conditions.
COVID-19,
COVID 19 CAN BE TRANSMITTED THROUGH
Respiratory Droplets: Spread through coughing, sneezing, talking, or breathing.Aerosols: Smaller particles that can remain suspended in the air, particularly in poorly ventilated spaces.Fomites: Surfaces contaminated with the virus, though this is a less common transmission route.
are a group of common viruses that can cause a range of illnesses affecting the respiratory tract, eyes, intestines, and urinary tract. They are particularly known for causing respiratory infections but can also lead to other conditions.
Adenoviruses
Redness, swelling, and discharge from the eyes.
Conjunctivitis (Pink Eye)
Hematuria and dysuria, primarily in immunocompromised individuals.
Urinary Tract Infections
Inflammation of the bronchial tubes, causing cough and mucus production.
Bronchitis
Runny nose, sore throat, cough, fever.
Common cold
Treatment for ADENOVIRUSES
There is no specific antiviral treatment for adenovirus infections; management focuses on relieving symptoms:Supportive Care: Adequate rest, hydration, and over-the-counter medications to alleviate symptoms like fever and pain.Hospitalization: In severe cases, such as pneumonia, especially in infants, elderly, or immunocompromised individuals.Eye Drops: For conjunctivitis, lubricating or antibiotic eye drops may be used to relieve symptoms and prevent bacterial superinfection.
versatile pathogens causing a variety of illnesses, from respiratory infections to gastroenteritis and conjunctivitis
Adenoviruses
Severe infection of the lungs, leading to fever, cough, and difficulty breathing.
Pneumonia
Characterized by the swelling of the nasal passages and the back of the throat
NASOPHARYNGITIS
Combination of sore throat, fever, and conjunctivitis, often seen in outbreaks among children.
Pharyngoconjunctival Fever
TRANSMISSION OF PATHOGENS THROUGH THE AIR
AEROSOL DROPLET
Most common mode of transmission among young children ans their families
FECAL-ORAL
Transimission may occur when coming to into contact with contaminated surfaces
DIRECT INOCULATION OF CONJUNCTIVAE BY FINGERS
Infection caused by different bacteria than the common ones that cause pneumonia
ATYPICAL PNEUMONIA