Skin Emergencies Flashcards
What is the management of anaphylaxis?
ABCDE
Adrenaline 1:1000 IM –> repeat after 5 mins if not better
Oxygen, fluids, monitor
IV chlorphenamine (antihistamine) + IV hydrocortisone
What is erythroderma?
Erythema covering > 90% of body surface
What are some causes of erythroderma?
Exfoliative erythroderma –> drugs
- allopurinol, antibiotics, carbamazepine, PPIs
Cutaneous T cell lymphoma
Erythrodermic psoriasis
What are some complications of erythroderma?
Tachycardia –> high output HF
Hyperthermia, chills
Lymphadenopathy
What is the general management of erythroderma?
Thermoregulation Correct fluids/electrolytes Treat any infection Emollients +++ Antihistmines for itch
Describe the pathophysiology in toxic epidermal necrolysis (TEN)
Keratinocyte necrosis –> large areas of epidermal and mucosal detachment
What % of body surface is effected in TEN?
> 30%
What is the management of TEN?
Withdraw causative drug Manage in burns unit/ICU Fluids + electrolytes Thermoregulation Minimise handling IV Ig
What is the presentation of Steven Johnson Syndrome (SJS)?
Prodrome of respiratory symptoms –>
Erosions of mucosal surfaces and skin
What % of body surface is effected in SJS?
Up to 10%
Which other features may be seen in SJS?
Haemorrhagic crusting of oral mucosa Conjunctivitis Pyrexia Target lesions, macules, blistering Dehydration
What is the course of SJS and how is it managed?
May persist for 4-6 weeks
Supportive treatment
What kind of rash in seen in meningococcal septicaemia?
Purpuric, non blanching
What is the treatment of suspected meningococcal septicaemia in primary care?
IM Benzylpenicillin
What is the treatment of suspected meningococcal septicaemia in secondary care?
ABCDE
IV Ceftriaxone