Dermatitis/Eczema Flashcards

1
Q

What are the characteristic features of any dermatitis rash?

A

ITCHY
Ill-defined
Erythematous
Scaly

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2
Q

What may been in the acute phase of the rash?

A
Papules, vesicles
Erythema
Spongiosis (oedema)
Ooze
Scaling
Crusting
Excoriations
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3
Q

What may be seen int he chronic phase of the rash?

A

Lichenification (thickening)
Elevated plaques
Increased scaling
Excoriations

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4
Q

What are the two different types of contact dermatitis?

A

Irritant

Allergic

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5
Q

Which type of hypersensitivity is contact allergic dermatitis?

A

Type 4 (delayed)

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6
Q

How do you diagnose contact allergic dermatitis?

A

Patch testing

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7
Q

Give some examples of causes of contact allergic dermatitis

A

Nickel, chemicals, plants, topical therapies

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8
Q

What is the process of having patch testing done?

A

Three appointments in 1 week

  • allergens put on back (first appointment)
  • allergens taken off back 48 hours later
  • reactions checked at 96 hours (third appointment)
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9
Q

How is irritant dermatitis different to allergic?

A

Non-specific physical irritation rather than specific allergic reaction
(difficult to tell the difference)

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10
Q

Give some examples of causes of irritant dermatitis?

A
Soap, detergent, cleaning products
Nappy rash (urine is irritant)
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11
Q

What is the typical distribution of atopic eczema?

A

Flexural (from of wrists, back of knees etc)

In infants –> cheeks and extensor surfaces

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12
Q

Which other conditions is atopic eczema associated with?

A

Asthma
Allergic rhinitis (hay fever)
Other allergies e.g. food

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13
Q

Which chronic changes are seen in atopic eczema?

A

Lichenification
Excoriation
Secondary infections

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14
Q

Which gene may be involved in eczema?

A

Filaggrin gene

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15
Q

What is the diagnostic criteria for atopic eczema?

A

ITCHING + 3 or more of:

  • visible flexural rash (cheeks/extensors in infants)
  • history of flexural rash
  • personal history of atopy (or first degree relative if < 4 years old)
  • generally dry skin
  • onset before age of 2
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16
Q

What is step 1 in the management of eczema?

A

Emollients alone

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17
Q

What is step 2 in the management of eczema?

A

Emollients + mild TCS (topical corticosteroid)

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18
Q

What is step 3 in the management of eczema?

A

Emollients + moderate TCS

+/- calcineurin inhibitor

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19
Q

What is step 4 in the management of eczema?

A

Emollients + potent TCS (short term)

+ specialist advice

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20
Q

What practical advice should be given to someone with eczema?

A

Avoid allergens/irritants
Emollients twice daily, even if eczema is fine
Avoid having sweaty skin
Use emollients in place of soaps in bath/shower

21
Q

When are ointments better than creams?

A

For dry, scaly, fissured or lichenified skin

22
Q

When are creams better than ointments?

A

For hot, inflamed, urticated skin

23
Q

What advice should be given for using ointments?

A

Use a spoon to take out of pot rather than fingers

–> doesn’t contain preservative so easily contaminated

24
Q

Name a mild TCS?

A

Hydrocortisone 1%

25
Name some moderate TCS?
Modrasone, Clobetasone, Butyrate 0.05%
26
Name some potent TCS?
Elocon, Betamethasone (betnovate), Valerate 0.1%
27
Name a very potent TCS?
Clobetasol proprionate 0.05%
28
What are some side effects seen with potent/very potent steroids?
Skin thinning --> striae Increased skin infections Telangiectasia + steroid acne (Betnovate) Systemic absorption --> poor growth, cushingoid features
29
How much surface are does a fingertip unit of TCS cover?
2 hand areas
30
How much TCS would be required to cover a whole adult body?
20 - 30g
31
How much emollient should be prescribed to last 1 week?
250 - 500g
32
What are calcineurin inhibitors and when are they used?
Potent anti-inflammatory agents without the steroid side effects Second like topical therapy for severe eczema
33
Give two examples of calcineurin inhibitors
Tacrolimus 0.1% | Pimecrolimus (face only)
34
Give some examples of physical therapies used in eczema?
Bangages - impregnated with zinc oxide paste +/- tar, antimicrobials Wet wrap therapy
35
What is the role for antihistamines in eczema?
No evidence for efficacy but sedative effects may help children to sleep if this is a problem --> contraindicated in children < 6 months
36
What does Staph aureus infected eczema look like?
Golden crust
37
How should you treat Staph aureus infected eczema?
``` Fucidin ointment (antibiotic) --> 5-10 days Consider antiseptics ```
38
How should eczema herpeticum be treated?
Emergency oral aciclovir
39
What is a rare complication of eczema herpeticum?
Encephalitis
40
What is seborrhoeic dermatitis?
pink scaly patches on scalp, eyebrows and nasolabial folds (oily areas) --> very common (stubborn dandruff)
41
Which conditions are associated with seborrhoeic dermatitis?
HIV and other immunosuppressive states
42
What does discoid eczema look like?
Discs of eczema, similar to psoriasis but not as well demarcated
43
What causes discoid eczema?
Chronic itch, rubbing and scratching | --> atopic eczema, itch from CKD
44
What is nodular prurigo?
Similar to discoid eczema, consequence of chronic itch
45
What is pompholyx eczema?
Itchy vesicular eczema on palms and soles
46
Which eczema is seen only on sun exposed sites?
Photosensitve eczema aka chronic actinic dermatitis
47
What is stasis eczema?
Aka venous eczema Seen in lower legs secondary to hydrostatic pressure, oedema and red cell extravasation --> chronic venous insufficiency, varicose veins, DVT
48
What does lichen simplex look like and what causes it?
Localised plaque of lichenified, chronic eczema | Response to scratching/rubbing over a long period of time