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Derm AM > Skin cancer > Flashcards

Skin cancer Flashcards

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Dermatology Board Prep flashcards
1
Q

What are the risk factors for BCC?

A 
UV radiation
Immunosuppression
Photochemotherapy
Chemical carcinogens
Ionising radiation
HPV
Familial cancer syndromes
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2
Q

What is the pathogenesis of BCC?

A

Locally invasive but rarely metastasise

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3
Q

What is the presentation of a BCC?

A

Pearly rolled edge with central ulceration
Telangiectasia and aborring vessels
Slow growing, rarely met

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4
Q

What are the management options for BCC?

A

Surgery- excision, Mohs surgery

Visomodegib

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5
Q

What are the indications for Mohs surgery in BCC?

A 
Site
Size
Subtype
Poor margins
Recurrent
Perineural/perivascular involvement
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6
Q

When is visomodegib indicated in BCC?

A

Localled advanced BCC not suitable fir surgery

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7
Q

What is SCC derived from?

A

Keratinising squamous epithelium, usually on sun exposed sites

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8
Q

What are the precursors to SCC?

A

Bowen’s disease- in situ SCC

Actinic keratosis- pre-cancerous area of thick, scaly or crusty skin

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9
Q

What is the presentation of actinic keratosis?

A

Sandpaper texture, normally felt before seen

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10
Q

What are the risk factors for SCC?

A 
UV radiation
Immunosuppression
Photochemotheraoy
Chemical carcinogens
Ionising radiation
HPV
Familial cancer syndromes
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11
Q

What is the presentation of an SCC?

A

Faster growing, tender, scaly/crusty/fleshy

Can ulcerate and bleed

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12
Q

What is the management of SCC?

A

Excision +/- radiotherapy

Follow up if high risk

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13
Q

What is the management of Bowen’s disease?

A

Topical treatment

Cryotherapy

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14
Q

What is the management of actinic keratosis?

A

Topical treatment

Cryotherapy

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15
Q

What are the types of melanoma?

A

Superficial spreading malignant melanoma= most common
Nodular melanoma- most aggressive
Lentigo maligna melanoma
Acral lentiginous/subungal melanoma= least common

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16
Q

What are the risk factors for melanoma?

A

UV radiation
Genetic susceptibility
Familial melanoma and melanoma susceptibility genes

17
Q

What is the ABCDE rule for melanoma?

A 
Asymmetry
Border- irregular
Colour- multiple
Diameter- large
Evolution- changes
18
Q

What are the criteria when diagnosing melanoma?

A 
7 point checklist
Major
-chenge in size
-change in shape
-change in colour
Minor
-diameter >5mm
-inflammation
-oozing/bleeding
-itch, altered sensation
19
Q

What is the management of melanoma?

A

Urgent wide local excision
Lymph node biopsy
+/- Chemo/immunotherapy
Regular followup

20
Q

What are some prognostic indicators for melanoma?

A

Breslow thickness- depth= most important
Mitotic rate >1
Ulceration

Derm AM (7 decks)

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