Skin Cancer Flashcards

1
Q

What are the 2 main types of skin cancer

A

Non-melanoma skin cancer

Melanoma

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2
Q

Where do the majority of non-melanoma skin cancers arise from

A

Keratinocytes within the dermis

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3
Q

Where do BCC arise from

A

Keratinocytes within the basal layer of the epidermis

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4
Q

Where do SCC arise from

A

Suprabasal layers

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5
Q

Where does melanoma arise from

A

pigment-forming cells (melanocytes) which are scattered along the basal layer of the epidermis

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6
Q

What is causing an increase in incidence of skin cancer in scotland

A

More sun exposure due to more holidays
More sunbed use
More diagnostic opportunity

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7
Q

What type of skin cancer is the fastest increasing cancer in scotland

A

Melanoma

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8
Q

How do BCCs usually present

A

As a translucent, slow growing lump or a non-healing ulcer

Painless

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9
Q

How do SCCs present

A

Warty or crusted growth or a non-healing ulcer
usually in sun exposed areas and they grow faster.
Pain and have the ability to spread

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10
Q

Twice as many young women get melanoma but more men die. True or false

A

true

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11
Q

The survival of melanoma depends on what

A

Tumour depth

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12
Q

The 5 year survival rate for melanoma is great if the depth of the tumour is less than what?

A

1mm

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13
Q

In terms of dermatology and melanoma, what does ABCDE stand for

A
Asymmetry
Border
Colour
Diameter
Evolution
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14
Q

Odd looking moles are often termed as what

A

Ugly duckling sign

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15
Q

Why do some sites become ulcerated

A

Due to the poor blood supply

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16
Q

Melanomas are sometimes confused with what

A

Pigmented BCC

17
Q

Are squamous cell carcinomas usually well differentiated or poorly differentiated

A

Well differentiated

18
Q

What are Actinic Keratoses

A

Precancerous skin lesions

19
Q

Describe the appearance of Bowen’s disease

A

erythematous plaque commonly found on the legs of older women

20
Q

What is common in a keratoacanthoma

A

Central crater

21
Q

What areas of the body are high risk for SCCs

A

Ear, scalp and lip

22
Q

Where are common metastatic areas of SCCs

A

Lymph nodes and bones

23
Q

What are some risk factors for skin cancer

A
Sun exposure
Genetic predisposition
Immunosuppression
HPV infection 
Smoking, ionising radiation
24
Q

How many skin types are there?

25
What does skin colour dictate
How sensitive you are to sun and your risk for getting skin cancer
26
Childhood sunburn increases the melanoma risk by what
4-fold
27
What type of genetic conditions increase your risk for developing skin cancer
Hereditary Type VII collagen deficiency Recessive dystrophic epidermolysis bullosa Naevoid basal cell carcinoma (Gorlin's syndrome) Oculocutaneous albinism Xeroderma Pigmentosum