Skin and Soft Tissue Infections Flashcards

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1
Q

List 6 types of infections commonly caused by water exposure.

A
Aeromonas
Edwardsiella tarda
Erysipelothrix rhusiopathiae
Vibrio vulnificus 
Mycobacterium marinarum
Vibrio parahaemolyticus
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2
Q

Define cellulitis.

A

Infection of the deeper dermis and fat layers after bacteria breach the skin barrier

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3
Q

What are the most common causes of cellulitis? (2)

A

Staph. aureus

Beta haemolytic streptococci, e.g.
-Strep. pyogenes

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4
Q

Describe the clinical features of cellulitis. (5)

What is the cellulitis triad? (3)

A

CELLULITIS TRIAD:
Oedema
Erythema
Warmth

OTHER FEATURES:
Skin changes
Fever

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5
Q

List 6 differential diagnoses for cellulitis.

A
Stasis dermatitis
Acute arthritis
Pyoderma gangrenosum
Hypersensitivity/drug reactions
DVT
Necrotising fasciitis
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6
Q

List 4 general risk factors for cellulitis.

List 8 local risk factors for cellulitis.

A
GENERAL RISK FACTORS:
Venous insufficiency
Lymphoedema
Pregnancy
White Caucasian
LOCAL RISK FACTORS:
Ulcers
Eczema
Athlete's foot
Burns
Surgical wounds
IVDUs
Trauma
Tattoos
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7
Q

Describe the classification of cellulitis.

HINT: there are 4 classes.

A

CLASS 1:
No sepsis
No co-morbidities

CLASS 2:
Possible systemic illness
At least one of:
-Peripheral vascular disease
-Obesity
-Venous insufficiency

CLASS 3:
Significant systemic illness
Unstable co-morbidities

CLASS 4:
Sepsis
Necrotising fasciitis
Unstable co-morbidities

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8
Q

In cellulitis, what can cause failure to respond to antibiotics? (3)

A
Resistant organisms (e.g. MRSA)
Underlying conditions (e.g. bone infection, abscess)
Incorrect diagnosis
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9
Q

When would you consider hospital admission in cellulitis patients? (4)

A

Severe, localised pain

Rapidly evolving skin lesions

SIRS:

  • HR 100+
  • RR 20+
  • Temp <36 or 38+
  • WCC <4 or 12+

Sepsis:

  • SIRS
  • Organ dysfunction (confusion, hypotension or RR 22+)
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10
Q

How would you treat cellulitis? Consider:

a) Mild cellulitis
b) Moderate cellulitis
c) Severe cellulitis

A

MILD CELLULITIS:
Flucloxacillin (oral)
-Duration: 7 days

MODERATE CELLULITIS:
Flucloxacillin (oral)
-Duration: 10 days

SEVERE CELLULITIS:
Flucloxacillin (IV)
Gentamicin (IV)
Clindamycin (IV)
-Duration: 10 days
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11
Q

Define erysipelas.

A

Infection of the upper dermis and superficial lymphatics in the skin

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12
Q

Define impetigo.

A

Superficial bacterial infection of the skin

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13
Q

Define necrotising fasciitis.

A

Severe inflammation and infection of the muscle sheath that leads to necrosis of the subcutaneous tissue and adjacent fascia

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14
Q

Define tinea.

A

A superficial dermatophyte infection of the epidermis, characterised by scaly, inflammatory or non-inflammatory patches

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15
Q

Define dermatophyte.

A

A pathogenic fungus that grows on skin, mucous membranes, hair, nails and other body surfaces

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16
Q

What are 2 other names for erythema infectiosum?

Define this disease.

A

Fifth disease, slapped cheek syndrome

A common, benign infection in children, caused by human parvovirus B19

17
Q

What is erysipelas caused by?

A

Group A streptococci (strep. pyogenes)

18
Q

Describe the clinical features of erysipelas.

A

Raised lesion
Clear line of demarcation
Elevated ASOT (antistreptococcal antibody titres)

Distribution:

  • Butterfly distribution in face (20%)
  • May involve the ear (cellulitis does not)
  • Legs (80%)
19
Q

How would you treat erysipelas?

A

Flucloxacillin or amoxicillin

PLUS

Gentamicin

20
Q

What is impetigo caused by? (4)

A

Primary infection:

  • Staph. aureus
  • Other staphylococci
  • Streptococci

Secondary infection:
-Herpes simplex virus

21
Q

Describe the initial features of necrotising fasciitis. (5)

Describe the later features of necrotising fasciitis.

A
INITIAL FEATURES:
Severe and out of proportion pain
Rapid spread
Systemically unwell patient
Erythema and swelling
No well-defined margins
LATER FEATURES:
Colour change: red/purple to blue/grey
Bullae development
Anaesthesia
Dusky skin
Necrosis
Skin crepitus 
Complete tissue destruction
22
Q

Which 5 antibiotics would you give for necrotising fasciitis?

A
Flucloxacillin IV
Benzylpenicillin IV
Gentamicin IV
Clindamycin IV
Metronidazole IV
23
Q

What organism most commonly infects animal bites?

A

Pasteurella

24
Q

Which organisms can cause tinea? (3)

Which is the most common?

A

Most common: trichophyton

Other causes:

  • Microsporum
  • Epidermophyton
25
Q

What causes erythema infectiosum?

A

Human parvovirus B19

26
Q

What causes hand, foot and mouth disease?

A

Coxsackie virus A16

27
Q

What is scalded skin syndrome also called?

What causes it?

A

Ritter’s disease; pemphigus neonatorum

Staph. aureus