skin and soft tissue infection Flashcards
what % people carriers of staph aureus
25%
antibiotic against staph aureus
fluclox
what antibiotics can be used in MRSA
vancomycin and teicoplanin
predisposing factors for skin and soft tissue infection
DM, chronic lymphoedema, venous ulcers, peripheral vascular disease, steroids, malnutrition
what is toxic shock syndrome
toxin secreting staph. exotoxin TSST-1- cytokine release fever and shock
signs TSS
diffuse macular rash, desquamation palms and soles
what is necrotising fasciitis
infection of the deep fascia and causing necrosis of the subcut tissue
what organism is responsible for nec fas
group A b haemolytic strep
signs Necrotising fasciitis
severe pain at site of infection, erythema, pain, crepitus. high CRP very high WCC
treatment necrotising fascitis
radical debridement +- amputation. benzylpenicillin and clindamycin