Skin

Question 1

State the 5 layers of epidermis

Answer 1

Stratum Corneum

Stratum Lucidum

Stratum Granulosum

Stratum Spinosum

Stratum Basale

Question 2

Describe stratum corneum (stratum lucidum)

Answer 2

30 day turnover

Consists of protein keratin

Desmosomes bind cells

No cells or organelles present

Disulphide linkages give strength

Conversion of keratohyalin to keratin

Question 3

Describe stratum granulosum

Answer 3

The presence of granules defines the layer

Consist of granules of keratohyalin

Question 4

Describe stratum spinosum

Answer 4

Spinous layer

Preparative layer for keratinisation

Created post-mortem:
Cells shrink but desmosome junctions ‘create’ spines

Question 5

Describe stratum basale (germinativum)

Answer 5

Continuous proliferation of stem cells to produce new keratinocytes

Bound to other cells by desmosomes

Bound to basement membrane by hemidesmosomes

Question 6

The stratum basale is also known as the

Answer 6

Stratum germinativum

Question 7

State the the 2 layers that make up the dermis

Answer 7

Papillary layer

Reticular layer

Question 8

State what the papillary layer is made up of

Answer 8

Loose connective tissue

Blood vessels

Nerve endings

Macrophages

irregular interface with epidermis

Question 9

State what the reticular layer is made up of

Answer 9

Dense irregular connective tissue

Collagen bundles in 3 planes

Elastic fibres