Random Flashcards

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1
Q

Man is made up of what % of water?

A

60%

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2
Q

The blood vessel capillary wall is permeable to everything except

A

Plasma proteins

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3
Q

Muscle contains __% water and fat contains __% water

A

70

10

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4
Q

Muscular males

A

Fat females

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5
Q

Dilution principle formula:

A

mass = volume x concentration

only plasma can be sampled

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6
Q

A rise in potassium concentration in the ECF can result in what cardiac condition?

A

Ventricular fibrillation (quivering of the heart)

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7
Q

What property of fatty acids make them flexible?

A

Fatty acids

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8
Q

Integral proteins are/ are not amphipathic

A

Are amphipathic (unlike peripheral proteins)

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9
Q

Transporter proteins:

Carrier proteins

A

Open to ECF, and then ICF. Typically moves larger molecules than channels e.g. glucose

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10
Q

Urea:

A

Penetrating particle

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11
Q

Ions:

A

Non-penetrating particles

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12
Q

Most sensitive organ to changes in tonicity?

A

Brain

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13
Q

Example of where positive feedback is seen:

A

Action potential

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14
Q

Plama is which component of blood?

A

Fluid component

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15
Q

Evans blue dye:

A

Attaches to plasma protein and helps to estimate the proportion of body water in the blood plasma

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16
Q

Mitochondria characteristics:

A
  • Their own circular DNA
  • Ribosomes (and so can synthesise most of their proteins)
  • Self-replicate
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17
Q

Cilia and flagella:

A

Cilia: Short, many present and move with stiff power stroke and flexible recovery stroke

Flagella: Long, usually only one or two present , movement is snake like

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18
Q

Enteric nervous system:

A

System of neurons that governs the function of the gastrointestinal tract.

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19
Q

White ramus:

A

Pre-ganglionic and myelinated

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20
Q

Grey ramus:

A

Post-ganglionic and unmyelinated

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21
Q

In the sympathetic nervous system, convergence and divergence lead to

A

Mass activation

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22
Q

Muscarinic receptors:

A
  • Parasympathetic

- They are metabotropic. They are g-protein coupled receptors

23
Q

Initial segment (axon hillock):

A

Triggers action potential

24
Q

Apart from producing the blood brain barrier, what else to astrocytes do?

A

Maintain the external environment for neurones

25
Q

What channels are found in the nodes of Ranvier between sheaths?

A

Sodium channels

26
Q

Cysteine:

A

Amino acid with sulphur in it

27
Q

4 pancreatic enzymes:

A

Trypsin
Elastase
Chymotrypsin
Carboxypeptidase

28
Q

In transamination reactions, one of the 2 substrates is often

A

Glutamate

29
Q
Fates of nitrogen - excretion:
1    Plants
2   Aquatic vertebrates  
3   Terrestrial vertebrates 
4   Animals (birds/reptiles)
5   Humans and great apes
A

1 Conserve almost all of their nitrogen
2 Release ammonia to their environment (passive diffusion from epithelial cells, active transport via gills)
3 Nitrogen excreted in the form of urea
4 Nitrogen excreted as uric acid
5 Nitrogen excreted as urea (from amino acids) and uric acid (from purines)

30
Q

Most common urea cycle defect:

A

Ornithine transcacrbamoylase (OTC)

31
Q

Complex I and II of the electron transport chain utilises

A

Fe-S centres

32
Q

1 ubiquinol molecule is oxidised to yield how many molecules of cytochrome c?

A

2

33
Q

Complex IV of the electron chain utilises

A

Fe-Cu centres

34
Q

Binding change mechanism

A

Binding change mechanism

35
Q

Type of reaction catalysed by lyases:

A

Forming double bonds or adding groups to double bonds

36
Q

Enzyme cofactors are are often what type of ion?

A

Metal ion

37
Q

Desolvation

A

Weak bonds between the substrate and enzyme essentially replace most or all of the hydrogen bonds between substrate and the aqueous solution

38
Q

Osmolarity definition:

A

The number of osmoles of solute per litre of solution

39
Q

Osmolality definition:

A

The number of osmoses of solute per kilogram of solvent

40
Q

Carbohydrates contribute to

A

Cell-cell communication.

ABO blood groups

41
Q

Even though the disaccharide sugar maltose barely comes from out diet, where can it be found?

A

Baby milk

42
Q

Why is sucrose termed as a non-reducing sugar?

A

No free anomeric carbon

43
Q

Branching frequency in glycogen and starch:

A

Glycogen: Every 8 - 12 residues

Starch (amylopectin): Every 24 - 30 residues

44
Q

Primary lymphoid organs:

A

Thymus, bone marrow and foetal liver

45
Q

Secondary lymphoid organs:

A

Lymph nodes and spleen

46
Q

The complement system brings about what 3 events?

A
  • Recruitment of inflammatory cells
  • Coating/opsonisation of bacteria
  • Lysis of bacteria
47
Q

The complement system is made up of how many serum proteins?

A

25

48
Q

Products of lipid digestion do what with bile salts?

A

Form mixed micelles (which release their contents when they approach the brush border)

49
Q

Chylomicron is what type of molecule?

A

Lipoprotein

50
Q

Free fatty acids are transported in lipoproteins in a complex with

A

Serum albumin

51
Q

Enzymes needed for fatty acid synthesis:

A
  • Acetyl CoA carboxylase

- Fatty acid synthase

52
Q

Fatty acid synthesis needs:

A

NADPH and acetyl CoA

53
Q

Product of fatty acid synthesis:

A

Palmitic acid