Skin

Question 1

6 main functions of skin?

Answer 1

1. protection
2. thermoregulation
3. maintain water content
4. sensory organ
5. energy storage
6. produces Vit. D

Question 2

3 major cell types in skin?

Answer 2

keratinocytes, fibroblasts, immune cells

Question 3

stratum corneum is made out of what?

Answer 3

dead cells (corneocytes) and lipid lamellae

Question 4

function of stratum corneum?

Answer 4

main layer of protection

Question 5

function of keratinocytes?

Answer 5

provide stratum corneum with new cells, secrete lipids for stratum corneum, secrete antimicrobial peptides

Question 6

function of fibroblasts?

Answer 6

form connective tissue by secretion of extracellular matrix

Question 7

3 types of exocrine glands?

Answer 7

sebaceous, eccrine, apocrine

Question 8

function of sebaceous glands?

Answer 8

secretion of oily sebum

Question 9

function of eccrine sweat glands?

Answer 9

thermoregulation

Question 10

function of apocrine sweat glands?

Answer 10

secrete protein-rich sweat into hair follicles

Question 11

2 types of tactile receptors?

Answer 11

meissner corpuscles, pacini corpuscles

Question 12

function of meissner corpuscles?

Answer 12

sense light touch

Question 13

function of pacini corpuscles?

Answer 13

sense coarse touch

Question 14

what is crucial for optimal skin barrier function?

Answer 14

organization of skin lipids in stratum corneum

Question 15

2 traits required for molecular penetration of skin?

Answer 15

1. moderately lipophilic (polar)

2. small size

Question 16

3 defense mechanisms of skin?

Answer 16

1. acidic pH
2. antimicrobial peptides
3. commensal bacteria

Question 17

2 common skin diseases?

Answer 17

atopic dermatitis, psoriasis

Question 18

symptoms of atopic dermatitis?

Answer 18

dry, red, itchy skin

Question 19

cause of atopic dermatitis?

Answer 19

genetic and environmental factors

Question 20

what is atopic dermatitis associated with?

Answer 20

atopic march

Question 21

cause of psoriasis?

Answer 21

immunological disorder