Sketchy Bacteria Flashcards
Gram- Indeterminate Bacteria:
What bacteria are under this category?
- Chlamydia trachomatis
- Coxiella bernetii
- Gardnerella vaginalis
- Mycoplasma pneumoniae
- Rickettsia
Gram- Indeterminate Bacteria:
How man Chlamydia bacteria are there?
3
- Chlamydia trachomatis
- Chlamydophila pneumoniae
- Chlamydophila psittaci
Gram- Indeterminate Bacteria:
What kind of bacteria are Chlamydia?
Obligate intracellular
-Meaning can only reproduce and survive inside the host organism (because cannot make their own ATP)
Gram- Indeterminate Bacteria:
Why does Chlamydia species have a poor gram stain?
Little or no muramic acid (component of peptodoglycan) in their cell walls
Gram- Indeterminate Bacteria:
Describe the life cycle of chlamydia?
- 1st Stage: Extracellular elementary bodies (infectious form)
- 2nd stage: Infects the body then becomes the reticular body, an active form replicating via binary fission
- 3rd stage: Releasing the bacteria in the elementary form
Gram- Indeterminate Bacteria:
What would you see under a microscope in cells infected with Chlamydia?
Inclusion bodies
Gram- Indeterminate Bacteria:
What stain is preferred with Chlamydia?
Giemsa stain, shows the inclusion bodies
Gram- Indeterminate Bacteria:
How is Chlamydia typically diagnosed?
NAAT-PCR
Gram- Indeterminate Bacteria:
What are the different types of Chlymidia Trachomatis associated with?
A-C: Blindness
D-K: STI
L1-L3: LGV
Gram- Indeterminate Bacteria:
How is Chlamydia D-K STI presented?
Watery discharge
Gram- Indeterminate Bacteria:
What are the complications of Chlamydia D-K STI?
PID: an ascending infections that can lead to cervicitis, salpingitis, pelvic pain, abscess formation, and scarring of uterine tubes that can cause infertility and ectopic pregnancy.
Gram- Indeterminate Bacteria:
What are the neonatal presentations if a woman with an active Chlamydia D-K infection gives birth?
Neonatal conjunctivitis (1-2 wks later) and neonatal pneumonia (staccato cough, really short, sudden bursts)
Gram- Indeterminate Bacteria:
What does Chlamydia L1-L3 cause?
Lymphogranuloma venerum, an infection mostly affecting the inguinal nodes
Look for painless ulcer progressing to tender inguinal lymphadenopathy.
Gram- Indeterminate Bacteria:
What disease is Chlamydia A-C associated with?
Trachoma (LEADING CAUSE OF BLINDNESS IN THE WHOLE WORLD)
Gram- Indeterminate Bacteria:
How is Chlamydia A-C spread?
Transmitted by hand to eye contact, or fomites
Gram- Indeterminate Bacteria:
What occurs if the immune system doesn’t fight the chlamydia infection as well as it should?
Reactive arthritis or Reiter syndrome
Mc Sacroiliac joint in the knee
Also look for uveitis and urethritis
“Can’t see, can’t pee, can’t climb a tree”
Gram- Indeterminate Bacteria:
What does Chlamydia Pneumoniae cause?
Atypical pneumonia/Walking pneumonia like Mycoplasma and Legionella though more common in elderly than young adults.
Chlamydia Psittaci can also trasmit pneumonia, look for hx of bird care typically seen in parrots/bird droppings.
Gram- Indeterminate Bacteria:
What is the treatment for Chlamydia?
- Macrolides like Azithromycin
- Tetracycline like Doxycycline
-*Give a single dose of Ceftriaxone to cover gonorrhea as well