Multisystem Flashcards
1
Q
Describe the amyloid type: AL
A
- derived from immunoglobulin light chains eg, Bence Jones protein in the blood or urine
- associated with Multiple myeloma
2
Q
Describe the amyloid type: AA
A
Associated with chronic inflammation eg, RA, TB
3
Q
Describe the amyloid type: A-beta
A
Main constituent of amyloid plaques in Alzheimer disease
4
Q
Describe the amyloid type: ATTR
A
Found in familial amyloid polyneuropathy (caused by a genetic mutation) and senile cardiac amyloidosis (caused by wild-type ATTR accumulation)
5
Q
Describe the amyloid type: A-beta2-M
A
Derived from beta2-microglobulin, associated with long-term hemodialysis
6
Q
Describe the amyloid type: IAPP (amylin)
A
Found in T2DM
7
Q
Describe the amyloid type: PrP
A
Misfolded prion protein found in Creutzfeldt-Jacob disease
