Skeletal Tissue and the Axial Skeleton Flashcards
Skeleton Overview
- Composed of 206 bones
Provides
o Support, protection, movement, mineral storage, blood cell production
Histology
- Skeleton formed primarily from connective tissues
o All CT contains cells and extra cellular matrix
o Matrix contains
Fibres
Ground Substance (between cells and fibres)
o Cartilage and bone tissue (different types of supportive CT)
Supportive Cartilage
Three Types include
o Hyaline Cartilage
o Fibrocartilage
o Elastic Cartilage
Function
- Provides basic template for the foetal skeleton before bone formation
- Binds and protects structures of the adult skeleton
- Has properties of rubber, can bear weight, flexible
Cartilage (Cells and Matrix)
Cells = chondrocytes
o Cyte = mature cell
o Found in spaces called lacunae
Matrix
o Contains ground substance (composes of proteoglycans, creates flexible, resilient structures
o Many collagenous fibres (for tensile strength)
Hyaline Cartilage
- Most abundant cartilage in the skeleton
- Located at epiphyses of long bones, anterior end of ribs and airways
- Matrix appears glass-like
- Collagenous fibers are not visible
Fibrocartilage
- Strongest of cartilages, many collagenous fibres
- Located in pad-like structures (knee menisci), intervertebral disks and pubic symphysis
Bone
- A hard CT
- Consists of cells and mineralised matrix
- Strength and rigidity allows bones to support organs
Cells include o Osteoblast (build bone) o Osteocyte (mature cell that maintains bone) o Osteoclast (breaks down bone)
Matrix of Bone Tissue
- 1/3 of bone matrix is collagenous fibres (provide strength and flexibility)
- 2/3 of bone matrix is inorganic matter
o 85% calcium phosphate salt
o 10% calcium carbonate - Inorganic salts resist compression, allow bones to support without sagging
Compact and Cancellous Bone
Compact
o Makes up the dense outer layer of bone
o Main structural unit = osteon
Spongy
o Consists of interconnecting plates of bone (trabeculae)
o Contain spaces filled with bone marrow
Compact Bone
- Contain collagenous fibres in criss-crossing arrangements for structural reinforcements
- Canaliculi link osteocytes to blood supply
Spongy Bone Anatomy
Porous lattice of bony struts called trabeculae
o Lacks true osteons
o Strong but light
o Cavities contain red marrow (source of new blood cells)
Found in abundance in short, flat and irregular bones
Periosteum
o Double-layered protective membrane lining external surface of bones
o Outer layer of fibrous CT
o Anchored to bone by Sharpey’s Fibres
o Inner osteogenic (bone forming) layer (contains osteoblasts and osteoclasts)
Endosteum
o Delicate membrane covering internal surfaces of bone
o Contains osteoblasts and osteoclasts
Diaphysis
- Tubular shaft that forms the axis of long bones
- Composed of compact bone
- Surrounds the medullary cavity (contains yellow marrow)
Epiphysis
- Expanded ends of long bones
- Exterior = compact bone, Interior = Spongy Bone
- Joint surface lined with articular (hyaline) cartilage
- In immature bones, epiphyseal plate separates the diaphysis from epiphyses
Short, Flat and Irregular Bone Membranes
- Thin plates of periosteum lined compact bone on the outside with endosteum lined spongy bone on the inside
- Contains red bone marrow (between trabeculae)
Bone Formation
- Before 8 weeks = embryonic skeleton is composed of membranes and hyaline cartilage
- Bone begins to ossify (initial regions = primary ossification centres)
Intramembranous Ossification
- Produces mostly flat bones of the skull
- Develops from a fibrous membrane
Endochrondral Ossification
- Produces most bones in skeleton below the skull
- Hyaline cartilage is template material
- Epiphyseal plate facilitates lengthwise growth of long bones until puberty
Bone Remodelling
- Dynamic living tissue that is constantly broken down and reformed
- Turnover allows the bone structure to meet changing physical stresses
Bone Resorption
o Osteoclasts degrade organic matrix
o Solubilise mineral matrix
Bone Deposition
o Osteoblasts secrete organic matrix
o Mineralisation follows
Articulations
- Condyle (rounded knob that articulates with another bone)
- Head (prominent expanded end of bone)
- Facet (smooth flat, slightly convex or concave surface)
Projections
- Epicondyle (projection superior to condyle)
- Trochanter (large processes on femur)
- Tubercle (small, rounded process)
- Tuberosity (rough elevated surface)
- Crest (narrow ridge)