Skeletal System Flashcards
(27 cards)
Define bone remodelling.
The ongoing replacement of old bone tissue by new bone tissue. consists of 2 processes.
Name the two processes involved in bone remodelling and what they do.
- bone deposition (addition of minerals and collagen fibres by osteoblasts)
- bone resorption (removal of minerals and collagen by osteoclasts)
List four bone cells that contribute to bone remodelling
- osteoprogenitor cells
- osteoblasts
- osteocytes
- osteoclasts
How do osteoprogenitor cells contribute to bone remodelling?
involved with cell division to become an osteoblast
How do osteoblasts contribute to bone remodelling?
bone formation - secrete collagen fibres and other organic components to build ECM (deposition)
How do osteocytes contribute to bone remodelling?
- maintain daily metabolism
* maintain mineral concentration of matrix
How do osteoclasts contribute to bone remodelling?
breakdown ECM (resorption, regulate calcium)
List the four zones that are present in the EPIPHYSEAL PLATE of a long bone.
- zone of resting cartilage
- zone of proliferating cartilage
- zone of hypertrophic cartilage
- zone of calcified cartilage
What occurs on the epiphyseal side of the epiphyseal plate during growth in length? (Include cells involved)
- interstitial growth of cartilage (mitosis)
* chondrocytes proliferate
What occurs on the diaphyseal side of the epiphyseal plate during growth in length? (Include cells involved)
- replacement of cartilage
- osteoclasts dissolve calcified cartilage
- invasion of osteoblasts to build bone
Which part of the long bone increases in length?
diaphysis
What are the four phases of bone fracture repair?
- Phase 1 - reactive
- Phase 2a - reparative
- Phase 2b - reparative
- Phase 3 - remodelling
Describe one event that occurs in PHASE 1 of bone fracture repair.
reactive - inflammation occurs bringing phagocytes to the area and osteoclasts remove damaged tissue
Describe one event that occurs in PHASE 2a of bone fracture repair.
reparative - chondroblasts produce fibrocartilage used to build a soft callus that bridges the fracture
Describe one event that occurs in PHASE 2b of bone fracture repair.
reparative - osteoprogenitor cells develop into osteoblasts that produce spongy bone that forms a hard callus
Describe one event that occurs in PHASE 3 of bone fracture repair.
remodelling - dead portions of fragments reabsorbed by osteoclasts
Why does healing occur faster in bone than cartilage?
because bone has blood vessels, cartilage does not
List the two criteria that structural classification (of joints) is based on.
- based on structural classification (presence of absence of synovial cavity + type of connecting tissue
- based on functional classification (based on movement)
Name the three STRUCTURAL classifications
- fibrous
- cartilaginous
- synovial
Describe FIBROUS structural classification of joints
- no synovial cavity
* dense, fibrous connective tissue
Describe the CARTILAGINOUS structural classification of joints
- no synovial cavity
* fibrocartilage or hyaline cartilage
Describe SYNOVIAL structural classification of joints
- contains synovial cavity
* hyaline cartilage called articular cartilage
Name three FUNCTIONAL classifications of joints
- synarthrosis
- amphiarthrosis
- diarthrosis
Describe SYNARTHROSIS
immovable fixed joint between bones connected by fibrous tissue
eg sutures of skull