Muscular System Flashcards
Name 3 functional groups of proteins involved in sarcomere structure
- contractile
- regulatory
- structural
How is the CONTRACTILE protein group involved with sarcomere contraction?
generate force during contraction
How is the REGULATORY protein group involved with sarcomere contraction?
help switch the contraction process on and off
How is the STRUCTURAL protein group involved with sarcomere contraction?
stabilise and binds together
List two proteins in the CONTRACTILE group
- myosin
* actin
List two proteins in the REGULATORY group
- tropomyosin
* troponin
List two proteins in the STRUCTURAL group
- titin
* dystrophin
Describe 3 events that occur in Step 1 (release of acetylcholine) in regulation of muscle contraction at neuromuscular junction.
- nerve impulse stimulates entry of Ca+2 through voltage-gated ion channels
- ACh is released into the synaptic cleft
- ACh diffuses across synaptic cleft from the motor neuron to the motor end plate.
Describe 2 events that occur in Step 2 (activation of ACh receptors) in regulation of muscle contraction at neuromuscular junction.
- ACh molecules bind to a receptor on the motor end plate
2. Opens Na+ channels and Na+ enters the muscle cell
Describe 4 events that occur in Step 3 (production of muscle action potential) in regulation of muscle contraction at neuromuscular junction.
- flow of Na+ makes inside of fibre more positive
- triggers a muscle action potential
- MAP propogates along sarcolemma into the T-tubules
- Sarcoplasmic Reticulum releases Ca+2 into sarcoplasm which attaches to the troponin
Describe 1 event that occurs in Step 4 (termination of ACh activity) in regulation of muscle contraction at neuromuscular junction.
- ACh is broken down by acetylcholinesterase (AChE)
Name two types of muscle fibres
- slow oxidative
* fast oxidative
Describe one characteristic of slow oxidative muscle fibres
lots of mitochondria, myoglobin and blood vessels
Describe one characteristic of fast oxidative muscle fibres
- few mitochondria and blood vessels
* low myoglobin
Descibe the method used for generating ATP for slow and fast oxidative muscle fibres
- slow oxidative - anaerobic respiration
* fast oxidative - anaerobic glycolysis