Skeletal Muscle And Nerve Tissue Histo Flashcards
Skeletal muscle
Striated Multinucleated Fatigable Voluntary Quick Strong
Myofiber
A group of myofibrils surrounded by endomysium
Muscle Cell
Myocyte
Myofibrils
Groups of sarcomeres
Sarcomeres
Contractile group made of actin and myosin myofilaments
Actin
Thin filaments
Made of f-actin monomers
Monomers come together to form actin filaments (in double stranded rings)
Uses nebulin to determine length of filament
Tropomyosin is intertwined in actin filament
Troponin is bound to tropomyosin blocking the myosin binding site
Myosin
Thick filaments
Has 2 heavy chains and 2 light chains
Heavy chains contain ATPase domain, actin binding sites, and myosin heads
Connected to Z disk via titin
Fascicle
Group of myofibers
Surrounded by perimysium
Muscle
Group of fascicles
Surrounded by epimysium
Sequence of what makes a muscle
Myosin and actin myofilaments Sarcomere Myofibril Myofiber Fascicle Muscle cell
Z disk
Sarcomere is Z disk to Z disk
Contains actin and myosin
M line
Where myosin attaches
H zone
Contains no thin filaments
Changes size during contraction
I band
Contains no myosin
Changes size during contraction
A band
From the end of one myosin head to the end of an adjacent myosin head
Does not change size during contraction
Muscle Contracttion
Ca2+ is released by the sarcolemma and binds to troponin
Causes conformational change
Troponin lets go of tropomyosin
Myosin binds to actin and crawls across actin
Myosin and actin do NOT change size
H zone and I band shorten
Z disk to Z disk becomes closer
all myofibrils in a muscle contract at the same time making the entire muscle shorten
Skeletal muscle fiber types
Type I
Type IIa
Type IIb
Type I muscle fiber
Slow, not very powerful Many mitochondria Great deal of myoglobin Aerobic respiration Slow fatiguability