Skeletal Muscle (2) Flashcards

0
Q

What are the different arrangements of skeletal muscle?

Give examples.

A
  • Circular: orbicularis oris
  • Convergent: Pectoralis major
  • Parallel: Sartorius
  • Unipennate: Exterior digitorum longus
  • Multipennate: Deltoids
  • Fusiform: Biceps brachii
  • Bipennate: Rectus femoris
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1
Q

What are the roles of skeletal muscle?

A
  • Movement
  • Stability of joints
  • Posture
  • Heat generation
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2
Q

What is fasciculation?

A
  • Muscle twitch
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3
Q

Explain what is meant by 1st, 2nd and 3rd class levers.

A
  • ALL: Force, load and fulcrum(pivot)
  • 1st: Force and load on opposite ends acting in different directions
  • 2nd: Force and load on the LHS upwards
  • 3rd: Force and load on RHS upwards
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4
Q

Give examples of 1st, 2nd and 3rd class levers

A
  • 1st: Skull/spinal cord
  • 2nd: Leg to foot
  • 3rd: Biceps
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5
Q

What are the different types of muscle groups and their roles?

A
  • Agonist: prime movers
  • Antagonist: opposes prime movers
  • Synergists: assist prime movers (neutralises extra movement)
  • Fixators: stabilises action of prime movers (non-moving joints)
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6
Q

What are the different types of muscle contraction?

A
  • Isotonic contraction: constant tension variable muscle length
  • Isometric: constant length, variable tension (hand grip)
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7
Q

What are the different types of isotonic contraction?

A
  • Concentric: muscle shortens (lifting load with arm)
  • Eccentric: muscle exerts a force whilst extended (downhill)
    can cause delayed-onset muscle soreness
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8
Q

What are type I, type IIa and type IIb muscle fibres?

A
  • Type I: slow oxidative
  • Type IIa: fast oxidative
  • Type IIb: fast glycolytic
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9
Q

Compare type I and type IIa muscle fibres.

A
  • Aerobic
  • High myoglobin levels
  • Red colour
  • Many mitochondria
  • Rich capillary supply - (type IIa /pink)
  • Fatigue resistant - (type IIa /moderate)
  • Endurance activities & posture -(type IIa /walking/sprinting)
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10
Q

How does type IIb differ to type IIa?

A
  • Anaerobic glycolysis
  • Low myoglobin levels
  • White colour
  • Few mitochondria
  • Poorer capillary supply
  • Rapidly fatigues
  • Short, intense movement.
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11
Q

What is proprioception?

A
  • Feedback control of movement.

- Muscles tell CNS how much force is being exerted.

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12
Q

What does a motor unit consist of?

A
  • Motor neurone and muscle fibres it innervates.
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13
Q

What is neuro-musculo communication?

A
  • ‘cross-talk’
  • signalling molecules communicate between nerves and muscles
  • atrophy of muscle/nerve leads to atrophy of corresponding neurone/muscle.
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14
Q

What is muscle tone?

A
  • Baseline tone in muscles at rest due to: motor-neurone activity/muscle elasticity
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15
Q

How is muscle tone controlled?

A
  • Motor control centres in brain

- Afferent fibre signals, originating in muscle.

16
Q

What is hypotonia?

A
  • Cerebral/spinal neural shock
  • Lesions of cerebellum
  • Lesions of sensory afferents from muscle spindles
  • Primary degeneration of muscle (myopathies)
17
Q

What is spatial summation?

A
  • More motor neurones activated
  • So more muscles recruited to develop more force
  • Reflex pathways have a role
18
Q

What is temporal summation?

A
  • Increased frequency of action potentials to muscle fibres

- If frequent enough then muscles are constantly contracted - tetanus

19
Q

What does EMG stand for and what does it show?

A
  • Electromyograph

- Muscle activity

20
Q

How does relaxation of muscles occur?

A
  • Ca pumped back into SR via Ca pumps

- Some Ca can bind to calmodulin (calcium binding messenger protein)

21
Q

How do muscle fatigue?

A
  • Depletion of muscle glycogen stores
  • Occurs within one minute of blood supply being disrupted
  • Intermittent claudication: pain during exercise that is relived once rested.
22
Q

How does muscle contracture occur?

A
  • State of continuous contraction

- Occurs when ATP’s depleted - myosin cross bridges can’t detach = rigor mortis