Sjogren's Syndrome

Question 1

What is Sjogren’s syndrome?

Answer 1

Autoimmune condition affecting exocrine glands causing symptoms of dry membranes.

Question 2

What are the symptoms of dry mucous membranes and what condition are they associated with?

Answer 2

1. Dry mouth/eyes/vagina

2. Sjogren’s syndrome

Question 3

What is the difference between primary and secondary Sjogren’s syndrome?

Answer 3

Primary - occurs in isolation

Secondary - occurs in relation to SLE/RA

Question 4

Which antibodies is Sjogren’s syndrome associated with?

Answer 4

Anti-Ro and Anti-La

Question 5

What is the Schirmer test and what condition does it identify?

Answer 5

1. Paper under lower eyelid, leave in then measure distance fluid has travelled.
2. Sjogren’s syndrome

Question 6

How is Sjogren’s syndrome managed?

Answer 6

1. Artificial tears and saliva
2. Vaginal lubricants
3. Hydroxychloroquine to halt progression

Question 7

What are the ocular complications of Sjogren’s syndrome?

Answer 7

Conjunctivitis and corneal ulcers

Question 8

What are the oral complications of Sjogren’s syndrome?

Answer 8

Dental cavities and candida infections

Question 9

What are the vaginal complications of Sjogren’s syndrome?

Answer 9

Candidiasis and sexual dysfunction

Question 10

What are the systemic complications of Sjogren’s syndrome?

Answer 10

Pneumonia, bronchiectasis, Non-Hodgkin’s lymphoma, peripheral neuropathy, vasculitis, renal impairment.