SIRS

Question 1

overwhelming inflammatory
response in the absence of
infection causing relative
hypovolemia and decreased
tissue perfusion.

Answer 1

Systemic inflammatory
response syndrome (SIRS):

Question 2

Four SIRS criteria:

Answer 2

• Tachycardia
- heart rate >90 beats/min

• Tachypnea
- respiratory rate >20
breaths/min)

• Fever or hypothermia
- temperature >38 or <36 °C

• Leukocytosis, leukopenia,
or bandemia
- white blood cells
>1,200/mm3, <4,000/mm3 or
bandemia ≥10%

Question 3

also known as quickSOFA is a bedside prompt
that may identify patients with suspected
infection who are at greater risk for a poor
outcome outside the intensive care unit (ICU).

Answer 3

Q SOFA

Question 4

3 component assessment system with:

Answer 4

o Systolic blood pressure ≤100 mmHg
o Highest respiratory rate ≥22 breaths per min
o Lowest Glasgow coma score <15

Question 5

Hypotension systolic BP <100 MmHg
Altered Mental Status
Tachypnea RR >22/min

Score of >2 criteria suggests a greater risk of poor outcome

Answer 5

q SOFA

Question 6

is a clinical syndrome
that complicates severe
infection and is characterized
by the systemic inflammatory
response syndrome (SIRS),
immune dysregulation,
microcirculatory
derangements, and end
-organ
dysfunction.

Answer 6

Sepsis

Question 7

is an illness severity score commonly used
in critical care medicine to predict mortality upon admission
to an intensive care unit.

Answer 7

Acute Physiology and Chronic Health Evaluation
(APACHE) score

Question 8

is well validated and
updated regularly, but its use is limited by the fact that
clinicians must pay to know and use its equation for
calculating death probability.

Answer 8

APACHE III

Question 9

is a
mortality prediction score that is based on the degree of
dysfunction of 6 organ systems.
▪ The score is calculated at admission and every 24 hours until
discharge, using the worst parameters measured during the
prior 24 hours.

stratifies mortality risk in ICU patients
without restricting the data used to admission values.

Answer 9

Sequential Organ Failure Assessment (SOFA)

Question 10

Is an objective and useful index assesses six systems in terms of the extent of
dysfunction on the first day of an intensive care unit (ICU)
stay. was designed to combine measurement of the
severity of multiple organ dysfunctions into a single score.

Answer 10

Logistic Organ Dysfunction (LOD) Score

Question 11

LODS: 6 systems

Answer 11

Neurologic, Cardiovascular, Renal,
Pulmonary, Hematologic, and Hepatic systems.