SÍNDROME NEFRÍTICO Flashcards

1
Q

FISIOPATOLOGÍA:

A
  • DEPÓSITO DE INMUNOCOMPLEJOS.
  • MB BASAL DEJA PASAR ERITROCITOS.
  • INFLAMACIÓN DISMINUYE LUZ.
  • ESPASMO EN A. AFERENTE DISMINUYE FLUJO GLOMERULAR.
  • ESTO ACTIVA SISTEMA R-A-A.
  • A II PROVOCA VASOCONSTRICCIÓN MÁS POTENTE.
  • SE ELEVAN SODIO URINARIO Y BUN.
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2
Q

CUADRO CLÍNICO:

A

-HEMATURIA MACRO/MICROSCÓPICA (CILÍNDROS HEMPATICOS).
-PROTEINURIA <2 G/DÍA.
AII:
-HIPERTENSIÓN SECUNDARIA.
-OLIGURIA/ANURIA.
-EDEMA.

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3
Q

ESTUDIOS DIAGNÓSTICOS SX NEFRÍTICO:

A
~EGO:
-PROTEINURIA <2 GR.
-CILINDROS CON ERITROCITOS DISMÓRFICOS.
~REL. BUN/CREA: 20:1.
~USG:
-REL. CORTEZA MÉDULA >2:1 = NEFRITIS.
~FENA (FRACCIÓN EXCRETADA DE NA) = <1%.
~OSM. URINARIA >500.
~COMPLEMENTO PARA CLASIFICAR.
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4
Q

CLASIFICACIÓN SEGÚN COMPLEMENTO:

A
  • COMPLEMENTO BAJO.

- COMPLEMENTO NORMAL.

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5
Q

CAUSAS DE SX NEFRÍTICO CON COMPLEMENTO BAJO EN:

A
  • LES.
  • GMN POSTESTREPTOCÓCICA.
  • HEP. C.
  • ENDOCARDITIS.
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6
Q

CAUSAS DE SX NEFRÍTICO CON COMPLEMENTO NORMAL EN:

A
CHURG-STRAUSS.
WEGENER.
PAM.
PHS.
PAN.
GOODPASTURE.
SX ALPORT.
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7
Q

DX ESPECÍFICO:

COMPLEMENTO NORMAL + ANCA (+) =

A

CHURG-STRAUSS.

PAM.

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8
Q

DX ESPECÍFICO:

COMPLEMENTO NORMAL + IC IGA =

A

PHS.

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9
Q

DX ESPECÍFICO:

COMPLEMENTO NORMAL + IC IGA + ANCA (+) =

A

WEGENER.

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10
Q

DX ESPECÍFICO:

COMPLEMENTO NORMAL + HB ALTA Y ANCA (-) =

A

PAN.

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11
Q

DX ESPECÍFICO:

COMPLEMENTO NORMAL + DAÑO A MB BASAL =

A
  • GOODPASTURE (AC VS COLÁGENO IV).

- SX ALPORT (DEFECTO EN COLÁGENO IV).

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12
Q

DX ESPECÍFICO:

COMPLEMENTO BAJO + CRIOGLOBULINAS IGM =

A

HEPATITIS C.

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13
Q

CAUSA MÁS FRECUENTE DE SX NEFRÍTICO EN MÉXICO:

A
  • POSTESTREPTOCÓCICA (12 Y 19).

- POR LES.

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14
Q

TTO SX NEFRÍTICO:

A
  • RESTRICCIÓN DE AGUA.
  • IECAS.
  • FUROSEMIDE.
  • TRATAR COMPLICACIONES (DIÁLISIS).
  • CAUSA DE FONDO.
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