Silicosis Flashcards
Silica
Crystalline SiO2 (quartz)
Where is quartz found
Sedimentary, Igneous and metamorphic rocks
Main mineral in desert sand and beaches
Quartz
Building products that contain silica
concrete, bricks
Cells that attack silica
Macrophages
What do macrophages do
- engulf silica to try and dissolve crystals
- carry silica into walls of the lung
Forms around dead cells
Scar tissue
Accumulation of excess fibrous connective tissue (fibrosis) leads to what
thickening of lung walls which causes reduced O2 supply to blood
Scar tissue formation caused by
Accumulation of excess fibrous connective tissue (fibrosis)
Consequence of scar tissue formation in lungs
Shortness of breath
Pulmonary fibrosis
Progressive, fatal lung disease - few survive more than 3-5yrs after diagnosis
Silicosis cause
Exposure to crystalline silica
Occupations known to expose workers to crystalline silica
- mining
- construction
- tunnel work
- masonry
- sand blasting
- glass manufacturing
- ceramics
- steel work
- quarrying
- stone cutting
Symptoms of acute silicosis
fever, sharp chest pain, breathing difficulty
Chronic silicosis symptoms
- cough
- breathing difficulty
- excess phlegm
- bronchitis-like
- wheezing
- abnormal chest x-ray