Signalling Flashcards
1
Q
Define juxtacrine signalling
A
Contact between inducing and responding cells
2
Q
Define paracrine signalling
A
Diffusion of inducers from one cell to another
3
Q
Define autocrine signalling
A
The same cell is both inducer and responder
4
Q
Define Matrix signalling
A
The matrix of one cell close to another sends the paracrine signal
5
Q
The five key steps of a signal transduction pathway
A
- Receptor activation
- Transcription factor activation
- Nuclear localization
- Chromatin decompaction
- Coupled initiation and 5’ capping
