Signaling Pathways of Endocrine Hormones

Question 1

cAMP

Answer 1

FLAT ChAMP

FSH, LH, ACTH, TSH, CRH, hCG, ADH (V2-receptor), MSH, PTH, calcitonin, GHRH, glucagon

Question 2

cGMP

Answer 2

BAD GraMPa

Think vasodilators

BNP, ANP, EDRF (NO)

Question 3

IP3

Answer 3

GOAT HAG

GnRH, Oxytocin, ADH (V1-receptor), TRH, Histamine (H1-receptor), Angiotensin II, Gastrin

Question 4

Intracellular receptor

Answer 4

PET CAT on TV

Progesterone, Estrogen, Testosterone, Cortisol,
Aldosterone, T3/T4, Vitamin D

Question 5

Receptor tyrosine

kinase

Answer 5

MAP kinase pathway

Think growth factors

Insulin, IGF-1, FGF, PDGF, EGF

Question 6

Nonreceptor tyrosine

kinase

Answer 6

JAK/STAT pathway

Think acidophils and cytokines

PIGGLET

Prolactin, Immunomodulators (eg, cytokines IL-2, IL-6, IFN), GH, G-CSF, Erythropoietin,
Thrombopoietin