PATH - Neuroendocrine Tumors Flashcards
1
Q
Neuroblastoma
A
Most common tumor of the adrenal medulla in children (usually
2
Q
Pheochromocytoma
A
Most common tumor of the adrenal medulla in
adults
Derived from chromaffin cells (arise from neural crest).
Most tumors secrete epinephrine, norepinephrine, and dopamine, cause episodic hypertension.
Symptoms occur in “spells”—relapse and remit
Episodic hyperadrenergic symptoms (5 P’s):
-Pressure ( BP)
-Pain (headache)
-Perspiration
-Palpitations (tachycardia)
-Pallor
LAB
INC catecholamines and metanephrines in urine
and plasma
TX
Phenoxybenzamine
