Side effects and Formulation

Question 1

Once glyceryl trinitrate tablets are open how long till they have to disposed?
A. 4 months
B. 3 months
C. 8 weeks
D. 10 days

Answer 1

C

Question 2

Once Dabigatran capsules are open how long after they are open must they be disposed of?
A. 4 months
B. 3 months
C. 8 weeks
D. 10 days

Answer 2

4 months according to Boehinger-Ihlem manufacturers

Question 3

Which CCB in this list must be kept in its packaging?
A. Amlodipine
B. Nifedipine
C. Verapamil
D. Felodipine
E. Diltiazem

Answer 3

(B)

Question 4

Which drug from the list cannot be handled crushed or broken by pregnant women?
A. Finasteride
B. Madopar dispersible tablets
C. Dabigatran
D. Nifedipine

Answer 4

A. Women should not handle crushed or broken finasteride tablets (5α-reductase inhibitor), as this may cause birth defects. EMC states because of the ability of the type II 5α -reductase-inhibitors to inhibit conversion of testosterone to dihydrotestosterone, these drugs, including finasteride, may cause abnormalities of the external genitalia of a male fetus when administered to a pregnant woman

Question 5

Which drug must women avoid contact with?
A. Cabergoline
B. Nifedipine
C. Glyceryl trinitrate
D. Dutasteride caps

Answer 5

(D) Dutasteride capsules (5α-reductase inhibitor) due to absorption through the skin(can affect fertility)

Question 6

Which drug from this list causes dermatitis when handling?
A. Cabergoline
B. Dutasteride
C. FINESTERIDE
D. Chlorpromazine

Answer 6

(D)

Question 7

Which medicines should be KEPT in their original packaging ?

Answer 7

Question 8

Which of the following can be a side-effect of desmopressin?
The SPC is provided here: https://www.medicines.org.uk/emc/product/171
Hypocalcaemia
Hypokalaemia
Hypomagnesaemia
Hyponatraemia
Hypophosphataemia

Answer 8

Hyponatremia

Question 9

Which drug causes pernecious anaemia

Answer 9

Metformin
Colchicine
PPI
H2-Antagonist
Nitrous oxide