Questions wronged

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Phenoxymethylpenicillin is used in sickle cell to reduce the incidences of pneumococcal infection. Hydroxycarbamide prevents acute onset of chest syndrome and the frequency the painful crisis occurs. Giving opioid in sickle cell crisis is important.

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If you have symptoms that could be caused by prostate cancer, you should visit a GP.

There’s no single, definitive test for prostate cancer. The GP will discuss the pros and cons of the various tests with you to try to avoid unnecessary anxiety.

The GP is likely to:

ask for a urine sample to check for infection
take a blood sample to test your level of prostate-specific antigen (PSA) – called PSA testing
examine your prostate by inserting a gloved finger into your bottom – called digital rectal examination

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Question 18

You need to be vigilant for signs of diabetic ketoacidosis when withdrawing insulin on patients also taking which medicine?

Dipeptidylpeptidase-4 inhibitor Glucagon-like peptide-1 receptor agonist
Metformin
Sodium glucose co-transporter 2 inhibitor Sulfonylurea

Answer 18

GLP-1 Agonist Diabetic ketoacidosis has been reported in patients with type 2 diabetes on a combination of a GLP-1 receptor agonist and insulin who had doses of concomitant insulin rapidly reduced or discontinued.

References:
https://www.gov.uk/drug-safety-update/glp-1-receptor-agonists-reports-of-diabetic-ketoacidosis-when-concomitant-insulin-was-rapidly-reduced-or-discontinued

Question 19

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A

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NSAIDs cause diarrhoae and stomach pain

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Propylene glycol

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Duloxetine is the only drug licensed for diabetic peripheral neuropathic pain specifically.

Side note: Pregabalin is licensed for CENTRAL and peripheral neuropathy.

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For psoriasis of the trunk and/or the limbs, a potent topical corticosteroid plus a topical vitamin D preparation must be prescribed (both applied once a day, but at different times of day). Betamethasone valerate 0.025% cream = moderate; clobetasone butyrate 0.05% cream = moderate; fluocinolone acetonide 0.0025%cream = mild; hydrocortisone acetate cream and ointment 0.5 to 2.5% = mild; mometasone furoate 0.1% cream = potent

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An angiotensin-converting enzyme (ACE) inhibitor (e.g., perindopril, ramipril, captopril, enalapril maleate, lisinopril, quinapril or fosinopril sodium) and a beta-blocker licensedfor heart failure (e.g., bisoprolol fumarate, carvedilol, or nebivolol) should be given as first-line treatment to reduce morbidity and mortality.% who got the answer correct: 48

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hypothyroidism causing decreased clearance of CK and decreased catabolism of statins

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5

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C

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Question 35

A regular patient from your community pharmacy has been discharged from hospital following a fall associated with hypoglycaemia. He is a 72-year-old man with Type 2 Diabetes who has recently had his medicines changed due to poor glycaemic control.When reviewing his prescriptionlist, which of the following medicines would you be most concerned about in relation to the risk of hypoglycaemia?Select one:A.DapagliflozinB.GlibenclamideC.GliclazideD.MetforminE.Pioglitazone

Answer 35

Question 36

Which inhaler preparations and aerosal device?
Which inhalers are once a day administration for both asthma and COPD

Answer 36

MDIS, EasiBreathe,Autohaler,Respimat
ONCE A DAY PREP:
Fluticasone/vilanterol (Ellipta)
Mometasone: 400 microgram (Twisthaler)
All LAMA/LABA Prep except Aclidinium/vilanterol(DuaKlir Genuair)
Ciclosonide

Question 37

What are the requirements for controlled drug requistion form?

Answer 37

B is incorrect

Question 38

What colour does sulfasalzine turn urine

Answer 38

Sulfasalazine is a yellow/orange color; people who take it may notice that their urine, tears, and sweat develop an orange tinge, which can stain clothing and contact lenses.

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H
MTX is renally excreted and amoxicillin reduces MTX excretion via competition at tubular secretion.

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In addition to cardiovascular and metabolic effects, beta-blockade inhibits Na(+)-K+ ATPase pumps controlling ion movement between muscle and plasma and thus may contribute to muscle fatigue through this mechanism.

Question 46

What are the legal requirements for sale pseudoepniphrine and epinephrine?

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Question 47

For tamsulosin OTC use what parameters must patient fit?

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The common, dose-dependent, reversible bone marrow suppression from chloramphenicol is a consequence of mitochondrial injury. The greater erythroid susceptibility to chloramphenicol appears to be a function of the endogenous mitochondrial amino acid pools.

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E

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Question 67

What is the reason why mesalazine and lactulose cannot be taken together?

Answer 67