Question wronged pt2

Question 1

A 60-year-old women is taking the following medication following recurrent deep vein thrombosis:
*Amlodipine 10 mg tablets once daily
*Apixaban 2.5 mg tablets twice daily
*Atorvastatin 20 mg tablets once daily
*Bendroflumethiazide 2.5 mg tablets once daily
She has hypertension which is controlled by her medication. She presents with severe facial pain and is diagnosed with trigeminal neuralgia. She is to commence treatment with Carbamazepine 100 mg tablets twice a day for the pain.Which of her existing medicines,if any, should be avoided when taking carbamazepine?oAmlodipine
oApixaban
oAtorvastatin
oBendroflumethiazideo
None –patient should be monitored and doses adjusted accordingly

Answer 1

oApixaban
And dabigatran-interaction is severe manufacture against use

Question 2

You are undertaking a medication review with a 72-year-old man, who was admitted to hospital the previous evening following a fall at their home. They are stabilised on warfarin at a dose of 3.5mg on Tuesdays and Fridays and 3mg on the remaining 5 days a week. During their review, they discuss their diet, lifestyle, and other medicines they take, with you.Which of the following is LEASTlikely to affect the patient’s INR control whilst on warfarin?oAddition of clarithromycin for a respiratory tract infection
oChronic diarrhoea
oDrinking grapefruit juice every morning
oIncrease in levels of kale and spinach in diet
oTaking a multivitamin supplement each day

Answer 2

Warfarin has multiple interactions including Vitamin K, clarithromycin and cranberry but not grapefruit. Grapefruit usually interacts with some statins.