Side Effects Flashcards
SSRI side effects
Sleep disturbance Headache Nausea GI bleeding Weight changes Sexual disturbance SIADH
TCA problem
Toxic, easy to over dose
Extrapyrimidal sx
Parkinsonism
Akathisia
Dystonia
Tardive dyskinesia
Parkinsonism
Rigidity
Bradykinesia
Tremor
Dystonia
Oculogyric crisis
Torticollis
Occulogyric crisis
Eye stuck in one direction
Torticollis
Neck stuck in one direction
Akathisia
Restlessness
Lithium SE
Fine Tremor (coarse in lithium toxicity) Metalic taste Kidney toxicity Thyroid toxicity Ebstein anamoly (cardiac defect) Polydipsia
Clozapine SE
Agranulocytosis (neutrophilopaenia)
Myocarditis
Sodium Valporate
Leukocytosis (high WBC) Teratogenic (neuro tubal defect: absolute no) Liver failure Alopecia Nystagmus
Neuroleptic malignant syndrome (NMS)
Autonomic nervous system disturbance Hyperthermia Normal pupil Hyporeflexia Rhabdomyolysis
NMS cause
Started an antipsychotic a few days ago
NMS mx
Supportive
NMS ix
CK raised
Serotonin syndrome cause
Taking more than 1 SSRI or SSRI with
Serotonin syndrome management
Ciproheptadin(serotonin antagonist)
Serotonin syndrome
ANS instability
Diaphoresis
Hyperreflexia
Dilated pupils
Refeeding syndrome Ix
Mg
K
Phosphate
Refeeding syndrome ptahophysiology
High insulin
Pushes all 3 ions intracellularly
Pabronex
All the B vitamins
Give for 3 days if asymptomatic
Give for as long as needed if withdrawing
Delirium tremens
2-3rd day of alcohol withdrawal
Tardive dyskinesia
involuntary, repetitive body movements eg
- grimacing
- sticking out the tongue
- smacking of the lips.
Amisulpride SE
High prolactin (eg galactrorrhoea)
seizure post alcohol time
36 hrs
Timing for first alcohol withdrawal sx
6-12 hrs
Sertraline
Used in Ischaemic heart disease
Citalopram
Gives LQTS
Fluoxetine
Used in kids under 18
Benzo overdose treatment
Flumazenil
Delirium tremens sx
Hallucination Coarse tremor Confusion/aggression Fever Tachycardia
Paroxetine use
PTSD
