Affective Disorders Flashcards

1
Q

Affective disorders

A

Mood disorders

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2
Q

Mood vs Affect

A

Mood is patient expressed mood

Affect is Dr’s impression of mood

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3
Q

Mania vs Hypomania

A

Mania: psychotic sx

Hypomania - no psychotic sx

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4
Q

Depression epidemiology

A

Mean onset 27 yrs

F>M

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5
Q

Depression RFs

A
Substance abuse
Lower socio-economic groups
Single / Separated / Divorced / etc
Parental deprivation
Negative beliefs
Poverty
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6
Q

Aetiology of Depression

A

Low 5HT
Low DA metabolism
Low NA
High cortisol

Hypothyroid

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7
Q

Cognitive triad of depression

A

Feeling Hopeless
Feeling Helpless
Feeling Worthless

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8
Q

Cluster A features of depression

A

Low mood
Anhedonia
Decreased activity/energy

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9
Q

Cluster B features of depression

A

Poor concentration
Guilt
Self harm thoughts
Disturbed sleep - often wake early

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10
Q

Auditory hallucinations in depression

A

Talk in second person - “you”

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11
Q

Auditory hallucinations in schizophrenia

A

Talk in third person - talk about them

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12
Q

Bereavement

A

Hallucinations common for 6 - 9 months

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13
Q

Depression average episode length

A

6 months

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14
Q

Percentage depression episode recurrence

A

80%

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15
Q

Mx of depression

A

Mild - psychological treatment first line

Severe - medication first line

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16
Q

Medications for depression

A
SSRI
SNRI
MAOI
Tricyclics
Lithium augmentation
ECT
17
Q

SSRIs

Selective Serotonin Reuptake Inhibitors

A

Citalopram

Sertraline

18
Q

SNRIs

A

Venlafaxine

19
Q

Tricyclic antidepressants

A

Amitriptyline

20
Q

MAOIs

A

Phenelzine
Tranylcypromine
Selegiline

21
Q

Primary use of Lithium

A

Mood stabiliser

22
Q

Types of Bipolar Affective Disorder

A

Type 1
Type 2
Rapid cycling

23
Q

Type 1 bipolar affective disorder

A

Manic or depressive episodes

24
Q

Type 2 bipolar affective disorder

A

Hypomanic or depressive episodes

25
Q

Rapid cycling bipolar affective disorder

A

4 episodes in 12 months of depression or mania or hypomania

26
Q

Mean age of onset of Bipolar

A

21

27
Q

Features of mania

A
Elated / Irritable
Grandiosity
Racing thoughts
Decreased need for sleep
Psychotic sx
28
Q

Olanzapine

A

Antipsychotic drug

29
Q

Risperidone

A

Antipsychotic drug

30
Q

Haloperidol

A

Antipsychotic drug

31
Q

Mx of bipolar affective disorder

A

Benzodiazepines - short term
Antipsychotic drugs
Mood stabilisers

32
Q

Lithium

A

Mood stabiliser

33
Q

Carbamazepine

A

Mood stabiliser

34
Q

Aripiprazole

A

Antipsychotic and mood stabiliser

35
Q

Psychotic sx

A

auditory hallucination

delusions grandeur

36
Q

Minimum duration of sx for depression diagnosis

A

At least 2 wks