Affective Disorders Flashcards
Affective disorders
Mood disorders
Mood vs Affect
Mood is patient expressed mood
Affect is Dr’s impression of mood
Mania vs Hypomania
Mania: psychotic sx
Hypomania - no psychotic sx
Depression epidemiology
Mean onset 27 yrs
F>M
Depression RFs
Substance abuse Lower socio-economic groups Single / Separated / Divorced / etc Parental deprivation Negative beliefs Poverty
Aetiology of Depression
Low 5HT
Low DA metabolism
Low NA
High cortisol
Hypothyroid
Cognitive triad of depression
Feeling Hopeless
Feeling Helpless
Feeling Worthless
Cluster A features of depression
Low mood
Anhedonia
Decreased activity/energy
Cluster B features of depression
Poor concentration
Guilt
Self harm thoughts
Disturbed sleep - often wake early
Auditory hallucinations in depression
Talk in second person - “you”
Auditory hallucinations in schizophrenia
Talk in third person - talk about them
Bereavement
Hallucinations common for 6 - 9 months
Depression average episode length
6 months
Percentage depression episode recurrence
80%
Mx of depression
Mild - psychological treatment first line
Severe - medication first line