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Symptoms + Treatment +diagnosis > Sickle Cell > Flashcards

Sickle Cell Flashcards

1
Q

Blood Film

A

Sickle cell shaped cells

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2
Q

What genes are missing in Sickle

A

HbA / HbA2

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3
Q

What genes are increased expressed

A

HbF + HbS

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4
Q

What do individuals with sickle cell trait have (gene)

A

HbS + HbA

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5
Q

Symptoms

A

Vaso-occlusion (sickle cell crisis)

Acute chest syndrome (dysnpea)

Dactylics mainly children

Jaundice + gallstones

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6
Q

Treatment for Sickle Cell patients

A

Life longprophylactin penicillin with folate replacement

BT transfusions +iron chelation

diet high in protein

Hydroxyurea (elevates HbF)

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7
Q

Treatment for SIckle Cell trait patients

A

Avoid triggers (stress /high altitude)

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8
Q

What heart problems can occur

A

Murmurs / tachycardia

convulsions / strokes

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9
Q

Why does sickle cell have high mortality/ mordbidity

A

bacterial / viral infections high from staph aureus

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10
Q

What can happen for growth in kids

A

Growth retardation

avascular necrosis of head of femur

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Symptoms + Treatment +diagnosis (10 decks)

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