Short virus topics T/F Flashcards
Porcine parvovirus 1 is transmitted
through the faecal-oral route.
True (+ boar semen)
Parvovirus vaccine usually induce
protection up to 6 months.
False (1 year)
Porcine parvovirus multiplies in
lymphoid tissue of the throat.
True
The Hoko pig virus does not occur in
Hungary.
False (occurs in Hong Kong, Great Britain, Transylvania, Hungary)
Colostral immunity against swine
parvovirus lasts for months.
True (6 months: vaccinate piglets
after 6 months of age)
Porcine Parvovirus infection causes reproduction problems in swine herds.
True (SMEDI – Return to oestrus, abortion, reduced litter size)
Swine parvovirus is rare, mainly in backyardherds.
False (Worldwide, Endemic in most herds)
Swine parvovirus is frequent, causing clinical disease in all age groups
False (Mainly results in reproductive disorders in 1st parity pigs)
Swine parvovirus is frequent, causing foetal damage only.
False (no foetal damage)
Swine parvovirus cause foetal damage and resp signs in first pregnant gilts.
False (Can cause respiratpry disease in adults but this is rare)
Swine herds infected with parvovirus should be excluded from further breeding.
False (Recovery → Lifelong immunity (allow natural seroconversion of gilts)
They should be sent for slaughter (pork with parvo).
False
Postpone first mating and vaccinate them (pork with parvo).
False? No need to postpone breeding → Vaccinate with inactivated (live), vaccines at 6 months of age
No vaccination is needed as clinical signs are mild.
False (Infection results in great economic losses → Reduced litter size etc. )
Spreads both horizontally and germinatively.
False (Transplacental infection of piglets → SMEDI)
Prevention of PPV – General preventative rules and vaccination are used.
True (Hygiene (virus shed in faeces & saliva)
Vaccination (after 6 months of age)
Neurological disorders are frequent in porcine parvovirus infections.
False (PPV-1 infection results in reproductive problems in 1st parity females)
The primary site of porcine parvovirus (PPV-1) replication is in the small intestines.
True
Porcine parvovirus (PPV-1) infection of seronegative pregnant animals can damage the foetus.
True (1st paritly pigs → Virus is able to cross placenta & cause foetal infection )
Porcine parvoviruses are genetically uniform.
False (PPV2)
PPV-1 induces diarrhea in suckling piglets.
False (Can cause systemic disease in neonates)
Porcine SMEDI can only be induced by parvoviruses.
False (A number of other infectious agents result in SMEDI= stillbirth, mummification, embryonic death, infertility)
Porcine HoKoviruses are only present in China.
False
Porcine parvovirus (PPV-1) vaccinations start at or after 6 months of age.
True (1st vaccination >6 months of age, 1-2x prior to breeding & repeat annually )
Piglets of sows seroconverted by PPV-1 are maternally protected for 6 months.
True (Hence why we don’t begin vaccination programmes until 6 months of age)
PPV-1 is endemic in most pig herds.
True (may disappear spontaneously in herds with <100 sows)
New variants of PPV1 may breakthrough the immune protection.
True
Canine parvovirus two known serotypes
True (CPV1+2)
Parvovirus in dogs 8 weeks of age cause high mortality.
True
The canine parvovirus antigen is structurally uniform.
False?
Canine parvovirus spreads rapidly, causing enteritis and fetal damage in all age groups.
False (Severe symptoms in young puppies between 3-8 weeks (litters from unvaccinated bitches) → Sudden death, myocardial damage, high mortality. In older pups (>8 weeks) & adults → Enteritis))
Canine parvovirus affects mainly young animals with bloody enteritis.
True (Acute gastroenteritis – Vomiting, severe bloody diarrhea, abdominal pain, dehydration, weight loss)
Canine parvovirus can cause heart muscle degeneration and fetal damage.
True (In utero infection, infection of pups <8 weeks or in pups born to unvaccinated bitches can result in myocardial infection, necrosis & myocarditis )
Clinical signs in canine parvoviral enteritis are mostly very mild and remain unnoticed.
False (High mortality, severe bloody diarrhea etc. )
In susceptible young dogs, parvovirus infection (CPV-2) cause high mortality.
True (CPV-1 is non-pathogenic)
Older dogs are usually seropositive to CPV-2.
True (Either due to previous infection or vaccination )
Subtypes of canine parvovirus (CPV-2) can cause panleukopenia in cats
True (Accounts for ~10% of all panleukopaenia cases)
Maternal antibodies usually protects for 2-3 weeks against canine parvovirus disease.
False (Up to 3-4 months (8-16 weeks))
Older dogs are usually seropositive for canine parvovirus
True (Either due to previous infection or vaccination )
Canine parvoviral disease is similar to that causes by pantropic coronavirus.
True (CCoV-1 → Vomiting & watery diarrhea in young dogs. CCoV-2 → Haemorrhagic enteritis, vomiting & ataxia in dogs aged 1.5-2 months (similar age group))
Canine parvoviruses form a single antigenic group.
False (CPV-1 → ∅ pathogenic
CPV-2 → CPV-2a & -2b subtypes)
Canine parvoviruses do not infect cats.
False (Certain CPV-2 subtypes can infect cats → 10% of all panleukopaenia cases)
Canine parvoviruses can replicate in the myocardium of young pups.
True (Targets rapidly dividing cells → SI crypt epithelium, lymphopoetic tissue & myocardial tissue in young pups)
Canine parvovirus attacks lymphoid cells.
True (Bone marrow, spleen, thymus & lymph nodes)
Canine parvovirus infection of susceptible dogs results high mortality.
True (High mortality (death within 2-3 days) in young pups between 3-8 weeks)
Canine parvovirus is shed with the faeces.
True (High titres shed with the faeces → Contaminates environment)
Leukopaenia is characteristic for successful CPV-2 infections.
True (Replication in lymphopoetic tissue → Leukopaenia, neutropaenia)
Maternal immunity against feline panleucopenia usually lasts for more than six months.
False (6 weeks)
Cat panleukopenia causes myocarditis in young animals
True
In Hungary, panleukopenia does not occur.
False (Occurs worldwide)
A feline panleukopenia virus mainly in the faeces.
True
A feline panleukopenia general infection, fever symptoms.
True
Feline panleukopenia occurs worldwide.
True
Feline panleukopenia can also be caused by a canine parvovirus.
True
Feline panleukopenia virus infection in dogs can cause acute diarrhoea.
False (Can infect dogs, but no diarrhea)
Hyperimmune serum can be used for the treatment of feline panleukopaenia.
True
Vaccinations against feline panleukopenia usually start at or after 2 months of age.
True (1st vaccination at 2 months of age (live, attenuated vaccine)
Maternal immunity protects kittens up to 6weeks so cannot vaccinate before this)
Aleutian mink disease is characterised by type III hypersensitivity
True
Aleutian mink disease virus is responsible for 10% of feline panleucopenia cases.
False (CPV2)
The mink Aleutian disease in mink and-enteritis is caused by the same virus.
False (Aleutian disease –amdoparvovirus
Mink enteritis - protoparvovirus)
The mink Aleutian disease does not occur in our country. (Hungary)
False (Worldwide)
VN test can be used to detect the Aleutian disease.
False (No virus neutralizing antibodies → Immunkomplexes → Type III hypersensitivity)
The agent of Aleutian Disease causes enteritis in older minks.
False (Older minks (mainly of the Aleutian genotype) → Hypergammaglobulinaemia, glomerulonephritis)
Vaccination against Aleutian Disease is achieved with inactivated vaccines.
False
(Can vaccinate against parvoviral enteritis of mink but not against Aleutian mink disease (prevention is by general epidemiological measures & eradication using test & slaughter programmes))
It is possible to vaccinate against Aleutian mink disease.
False (∅ Tx, ∅ vaccine (can vaccinate against parvoviral enteritis in mink – annual vaccination is recommended))
Mink parvoviral enteritis is characterised by fever and high mortality.
True
Non-specific signs (incl. fever) & acute gastroenteritis, with up to 80% mortality in young, susceptible animals
Live vaccinea are used against Aleutian mink disease.
False (No vaccines)
Ferrets can also be infected by the aleutian mink disease.
True (And other Mustelidae (e.g. weasels))
Aleutian mink disease is usually acute.
False (Chronic appearance, slowly developing with an incubation time of 4-6 weeks)
Aleutian mink disease can result in interstitial pneumonia in young animals.
True (Young mink (kits) may die from acute interstitial pneumonia)
Aleutian mink disease is characterized by a type-I hypersensitivity.
False (Type-III (immune-complex formation)
Clinical symptoms of the disease Derzsy typically occurs within 3 weeks of age
True (<5weeks)
The Derzy disease pathogen only infects geese.
False (Geese and muscovy ducks)
The Derzsy s disease infects Elderly and young geese.
False (<5w but older birds can become symptomless carriers)
The Derzsy disease virus passes into the egg.
True
Derzsy´s disease (goose parvovirus) spreads horizontally and via eggs.
True (horizontally and vertically)
In Derzsy´s disease, primary replication occurs in the gut
True (PO infection → SI epithelium)
Derszy´s disease can cause disease in both old and youngs
False (Only causes clinical disease in birds <5 weeks of age with up to 100% mortality in birds <7-10 days (progressive resistance develops and losses are negligible by 4-5 weeks of age)
Symptoms of Derszy´s and hydropericardium-hepatitis syndrome are similar in geese
True?